Validation Data-Located Modification for the Multilevel Analysis of Miscategorized Nominal Response with Covariates Subject to Measurement Error

IF 0.8 Q3 STATISTICS & PROBABILITY
Maryam Ahangari, Mousa Golalizadeh, Zahra Rezaei Ghahroodi
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引用次数: 0

Abstract

In many longitudinal and hierarchical epidemiological frameworks, observations regarding to each individual are recorded repeatedly over time. In these follow-ups, accurate measurements of time-dependent covariates might be invalid or expensive to be obtained. In addition, in the recording process, or as a result of other undetected reasons, miscategorization of the response variable might occur, that does not demonstrate the true condition of the response process. In contrast with binary outcome by which classification error occurs between two categories, disorderliness in categorical outcome has more intricate impacts, as a result of the increased number of categories and asymmetric miscategorization matrix. When no modification is made, insensitivity of errors in either covariate or response variable, results in potentially incorrect conclusion, tends to bias the statistical inference and eventually degrades the efficiency of the decision-making procedure. In this article, we provide an approach to simultaneously adjust for misclassification in the correlated nominal response and measurement error in the covariates, incorporating validation data in the estimation of misclassification probabilities, using the multivariate Gauss–Hermite quadrature technique for the approximation of the likelihood function. Simulation results demonstrate the effects of modifying covariate measurement error and response misclassification on the estimation procedure.

对带有测量误差变量的误分类名义响应进行多层次分析的验证数据定位修正法
摘要 在许多纵向和分层流行病学框架中,有关每个人的观察结果都会随着时间的推移被反复记录。在这些随访中,对随时间变化的协变量的精确测量可能无效或昂贵。此外,在记录过程中,或由于其他未被发现的原因,可能会出现反应变量的误分类,这并不能说明反应过程的真实情况。与二进制结果相比,分类结果中的分类错误发生在两个类别之间,而分类结果中的无序性由于类别数量的增加和不对称的误分类矩阵而产生更复杂的影响。如果不进行修正,协变量或响应变量的误差不敏感,就可能导致错误的结论,使统计推断产生偏差,最终降低决策程序的效率。在本文中,我们提供了一种同时调整相关名义响应中的误分类和协变量中的测量误差的方法,将验证数据纳入误分类概率的估计中,使用多元高斯-赫米特正交技术来逼近似然函数。模拟结果表明了修改协变量测量误差和响应误分类对估计程序的影响。
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来源期刊
Mathematical Methods of Statistics
Mathematical Methods of Statistics STATISTICS & PROBABILITY-
CiteScore
0.60
自引率
0.00%
发文量
2
期刊介绍: Mathematical Methods of Statistics  is an is an international peer reviewed journal dedicated to the mathematical foundations of statistical theory. It primarily publishes research papers with complete proofs and, occasionally, review papers on particular problems of statistics. Papers dealing with applications of statistics are also published if they contain new theoretical developments to the underlying statistical methods. The journal provides an outlet for research in advanced statistical methodology and for studies where such methodology is effectively used or which stimulate its further development.
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