Modeling of Quantum Yields, Structure and Function of Cytochrome C and Cardiolipin: Its Enzymatic Activity and Free Radical Processes

IF 0.9 4区化学 Q4 CHEMISTRY, PHYSICAL

High Energy Chemistry Pub Date : 2023-12-23 DOI:10.1134/s0018143923080155

I. N. Levchenko, G. K. Vladimirov, I. V. Volodyaev, Y. A. Vladimirov

引用次数: 0

Abstract

Quantum yields, structure, and enzymatic activity points of coumarin–activated C-334 chemiluminescence of lipid peroxidation processes under the action of cytochrome C and cardiolipin complex in aqueous medium and in nonpolar environment were modeled. It is presented for consideration that: (1) quantum yields are significantly higher in the presence of the physical activator coumarin C-334 than in the case of its own unactivated luminescence; (2) enzymatic activity depends not only on the concentration of cytochrome C but also on the percentage ratio between its native and partially denatured forms.

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细胞色素 C 和心磷脂的量子产率、结构和功能建模：其酶活性和自由基过程

摘要模拟了在水介质和非极性环境中，细胞色素 C 和心磷脂复合物作用下，香豆素激活的 C-334 化学发光对脂质过氧化过程的量子产率、结构和酶活性点。结果表明(1) 在物理激活剂香豆素 C-334 的存在下，量子产率明显高于其自身未激活发光的情况；(2) 酶活性不仅取决于细胞色素 C 的浓度，还取决于其原生形式和部分变性形式之间的百分比率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

High Energy Chemistry 化学-物理化学

CiteScore

1.50

自引率

28.60%

发文量

审稿时长

6-12 weeks

期刊介绍： High Energy Chemistry publishes original articles, reviews, and short communications on molecular and supramolecular photochemistry, photobiology, radiation chemistry, plasma chemistry, chemistry of nanosized systems, chemistry of new atoms, processes and materials for optical information systems and other areas of high energy chemistry. It publishes theoretical and experimental studies in all areas of high energy chemistry, such as the interaction of high-energy particles with matter, the nature and reactivity of short-lived species induced by the action of particle and electromagnetic radiation or hot atoms on substances in their gaseous and condensed states, and chemical processes initiated in organic and inorganic systems by high-energy radiation.