Efficacy and Predictors of Success of Esophageal Hydraulic Balloon Dilation in Patients With and Without Previous Foregut Surgery

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Anh D. Nguyen , Austin Dickerson , Jesse Zhang , Ashton Ellison , Chanakyaram A. Reddy , Daisha J. Cipher , Rhonda F. Souza , Stuart J. Spechler , Vani JA Konda
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引用次数: 0

Abstract

Background and Aims

The advantages of esophageal hydraulic balloon dilation include the ability to dilate up to 30 mm without fluoroscopic guidance and real-time display of the esophagogastric junction diameter during dilation. We aimed to explore the safety and efficacy of esophageal hydraulic balloon dilation in patients with and without previous foregut surgery, as well as to evaluate for predictors of clinical success.

Methods

We reviewed our database for patients who had esophageal hydraulic balloon dilation, and patients were divided into those with and without previous foregut surgery. Clinical success was determined by improvement in Eckardt/Brief Esophageal Dysphagia Questionnaire scores or, if not available, by physician assessment documented in the medical records. Technical success was defined as the ability to successfully perform esophageal hydraulic balloon dilation with visualization of the waist and stabilization of the balloon. Univariate analysis and logistic regression were used to evaluate predictors of clinical success after dilation.

Results

Among 80 patients who had esophageal hydraulic balloon dilation (36 without and 44 with previous foregut surgery), clinical success was achieved in 48% of patients without previous foregut surgery (43% in achalasia and 73% in esophagogastric junction outflow obstruction) and 83% of patients with previous foregut surgery (87% in surgically treated achalasia and 80% in patients without achalasia with previous fundoplication). Technical success was achieved in 86% of patients without previous foregut surgery and 98% in patients with previous foregut surgery. There was 1 esophageal perforation (1.3%). Opiate use was a negative predictor of clinical success.

Conclusion

Clinical success rates after esophageal hydraulic balloon dilation differ depending on the patient's foregut surgery history. Opiate users appear to have a lower clinical success rate compared with nonusers.

食道液压球囊扩张术对前肠手术患者和未接受前肠手术患者的疗效和成功预测因素
背景和目的食管液压球囊扩张术的优点包括无需透视引导即可扩张达 30 毫米,并能在扩张过程中实时显示食管胃交界处的直径。我们的目的是探讨食管液压球囊扩张术在既往接受过和未接受过前肠手术患者中的安全性和有效性,并评估临床成功的预测因素。方法我们回顾了数据库中接受过食管液压球囊扩张术的患者,并将患者分为既往接受过和未接受过前肠手术的患者。临床成功与否取决于 Eckardt/Brief 食管吞咽困难问卷评分的改善情况,如果没有,则取决于病历中记录的医生评估。技术成功的定义是能够成功进行食管液压球囊扩张术,并能看到腰部和稳定球囊。采用单变量分析和逻辑回归评估扩张术后临床成功的预测因素。结果 在 80 位接受食管液压球囊扩张术的患者中(36 位既往未接受过前庭手术,44 位接受过前庭手术),既往未接受过前庭手术的患者中有 48% 获得了临床成功(贲门失弛缓症患者为 43%,食管胃交界处流出道梗阻患者为 73%),既往接受过前庭手术的患者中有 83% 获得了临床成功(手术治疗的贲门失弛缓症患者为 87%,既往接受过胃底折叠术的非贲门失弛缓症患者为 80%)。86%未接受过前庭手术的患者和98%接受过前庭手术的患者取得了技术成功。有 1 例食道穿孔(1.3%)。结论食管液压球囊扩张术后的临床成功率因患者的前肠手术史而异。鸦片制剂使用者的临床成功率似乎低于非使用者。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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