Modern approaches to the choice of schemes for eradication of Helicobacter рylori infection (based on the materials of the consensus meeting "Maastricht-VI")

A. Sheptulin, S. Kardasheva, A. A. Kurbatova
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Abstract

The article presents an analysis of the provisions of the consensus meeting “Maastricht-VI”, dedicated to the treatment  of Helicobacter pylori (H. pylori) infection. The expediency of preliminary testing for H. pylori sensitivity to antibiotics is emphasized. Since this strategy has not yet been implemented in everyday clinical practice, empirical therapy is often carried  out based on the results of the assessment of H. pylori resistance to antibiotics in this region. The sequence of administration of  eradication regimens of the 1st, 2nd, 3rd, 4th lines, optimal duration of treatment, new therapy regimens (with rifabutin, double  therapy with proton pump inhibitors and amoxicillin in high doses) are considered. The implementation of the new consensus  meeting will contribute to improving the results of eradication therapy of H. pylori infection.
选择根除рylori螺旋杆菌感染方案的现代方法(根据 "马斯特里赫特-VI "共识会议的材料编写)
文章分析了 "马斯特里赫特-VI "共识会议的规定,该会议专门讨论了幽门螺杆菌(H. pylori)感染的治疗问题。文章强调了对幽门螺杆菌抗生素敏感性进行初步检测的紧迫性。由于这一策略尚未在日常临床实践中实施,因此通常根据该地区幽门螺杆菌对抗生素的耐药性评估结果进行经验性治疗。会议考虑了第一、二、三、四线根除方案的用药顺序、最佳疗程、新的治疗方案(利福布汀、质子泵抑制剂和大剂量阿莫西林的双重治疗)。新共识会议的实施将有助于改善幽门螺杆菌感染根除疗法的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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