O. Isaykina, K. A. Vekhova, G. S. Drobotov, R. A. Takhirov, M. A. Isaykina, V. M. Gorbunov
{"title":"Association of cognitive impairment and arterial hypertension","authors":"O. Isaykina, K. A. Vekhova, G. S. Drobotov, R. A. Takhirov, M. A. Isaykina, V. M. Gorbunov","doi":"10.14412/2074-2711-20236-4-9","DOIUrl":null,"url":null,"abstract":"Impaired cognitive function (CF) is a common manifestation of brain damage as a target organ of arterial hypertension (AH). The presence of hypertension in middle age increases the risk of developing cognitive impairment (CI) and dementia in old age. At the same time, changes in certain indicators characteristic of AH may serve as predictors of CI and dementia in the future. The review presents data on the effects of endothelial dysfunction and increased arterial stiffness on CF. The small number of papers on the effects of hypertension in middle-aged people on the development of CI emphasizes the importance of investigating this topic, as the incidence of CI in young and middle-aged people has increased in recent years.","PeriodicalId":19252,"journal":{"name":"Neurology, neuropsychiatry, Psychosomatics","volume":"50 45","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurology, neuropsychiatry, Psychosomatics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14412/2074-2711-20236-4-9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Impaired cognitive function (CF) is a common manifestation of brain damage as a target organ of arterial hypertension (AH). The presence of hypertension in middle age increases the risk of developing cognitive impairment (CI) and dementia in old age. At the same time, changes in certain indicators characteristic of AH may serve as predictors of CI and dementia in the future. The review presents data on the effects of endothelial dysfunction and increased arterial stiffness on CF. The small number of papers on the effects of hypertension in middle-aged people on the development of CI emphasizes the importance of investigating this topic, as the incidence of CI in young and middle-aged people has increased in recent years.
认知功能受损(CF)是动脉高血压(AH)靶器官脑损伤的常见表现。中年时出现高血压会增加老年时出现认知功能障碍(CI)和痴呆症的风险。同时,动脉高血压某些特征指标的变化可作为未来认知障碍和痴呆症的预测指标。综述介绍了内皮功能障碍和动脉僵化增加对 CF 影响的数据。关于中年人高血压对 CI 发病影响的论文数量较少,这强调了研究这一课题的重要性,因为近年来中青年人的 CI 发病率有所上升。