A Unique Case of Primary Subfrontal Lobe Meningioma with Intraorbital Extension

Uzma Panhwer, Bushra Shamim, Nimra Ali, Areeba Ahmed, Rida e Zainab
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Abstract

Introduction: Meningiomas, tumors originating from the meninges covering the brain, are typically considered benign. They primarily develop from arachnoid cap cells within the meninges and can manifest as primary orbital meningiomas (affecting structures like the optic nerve sheath) or secondary orbital meningiomas that extend from intracranial origins, such as the sphenoid wing and rarely from frontal lobe as in our case. Case Presentation: This report documents a very rare case where a meningioma emerged in the subfrontal lobe of the brain and subsequently spread to the orbit. The presence of such malignant variants in the orbit poses unique diagnostic challenges due to their potential to compress critical adjacent brain structures. Impact on Orbital Structures: The extension of these tumors into the orbit can have significant consequences, affecting structures like the cavernous sinus, superior orbital fissure, intraorbital contents, and the optic nerve. This further complicates their surgical management, given their proximity to essential neurological systems. Conclusion: This case study underscores the atypical growth pattern of malignant meningioma and highlights the complexities associated with identifying and treating meningioma with orbital extensions. The propensity of these tumors to impact vital brain structures necessitates a comprehensive approach to their diagnosis and management.
原发性额叶下脑膜瘤伴眶内扩展的独特病例
简介脑膜瘤是源于覆盖大脑的脑膜的肿瘤,通常被认为是良性的。它们主要由脑膜内的蛛网膜帽细胞发展而来,可表现为原发性眼眶脑膜瘤(影响视神经鞘等结构)或继发性眼眶脑膜瘤,后者从颅内起源(如蝶骨翼)延伸而来,很少像我们的病例那样从额叶延伸而来。病例介绍:本报告记录了一个非常罕见的病例,脑膜瘤出现在大脑额叶下,随后扩散到眼眶。由于这种恶性变体有可能压迫邻近的重要脑结构,因此在眼眶中出现这种恶性变体给诊断带来了独特的挑战。对眼眶结构的影响:这些肿瘤扩展到眼眶会造成严重后果,影响海绵窦、眶上裂、眶内内容物和视神经等结构。由于这些肿瘤靠近重要的神经系统,这使得手术治疗更加复杂。结论:本病例研究强调了恶性脑膜瘤的非典型生长模式,并突出了识别和治疗眼眶扩展脑膜瘤的复杂性。这些肿瘤容易影响重要的脑部结构,因此有必要采用综合方法对其进行诊断和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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