Research Centre for Nano-Materials and Energy Technology (RCNMET), School of Science and Technology, Sunway University, No. 5, Jalan Universiti

S. Reasmyraj, A. Syafiq, B. Vengadaesvaran, M. S. Ahmad, Nasrudin A. Rahim Rahim, P. Hassandarvish, Sazaly Abubakar, A. K. Pandey
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Abstract

Disease epidemics may spread quickly and easily throughout nations and continents in our current global environment, having a devastating effect on public health and the world economy. There are over 513 million people worldwide have been infected and more than 6.2 million have died due to SARS-CoV-2. There are treatments but no cures for most viruses. Nevertheless, the spread of viruses can be limited by introducing antiviral coatings on public area surfaces and personal protective equipment (e.g., face masks). This work aims to fabricate a polymer-based coating with acrylic resin as a binder that possesses great antiviral activity against the Feline coronavirus (FCov). The chosen polymer Polyethylene glycol (PEG) is used as an antiviral agent because it contains “green” chemistry benefits such as non-toxicity, inexpensive, readily recyclable, safe, natural, non-flammable, biocompatible, and biodegradable. The PEG/acrylic coating systems of different weight percentages were coated on the glass substrates by spray-coating method and cured at room temperature for 24 hours. The developed PEG/acrylic coating system that contains 20 wt% of PEG exhibits the highest anti-viral activities, 99.9% against FCov compared to the other weight percentages. From this study, it has been observed that hydrophilicity of the coating plays an important role in the antiviral activity. The developed coating has the hydrophilic property in which the contact angle was measured at 83.28 ± 0.5°. The FTIR reveals that there are no any existing toxic components or new components contained in the coating samples.
双威大学科技学院纳米材料与能源技术研究中心(RCNMET),地址:No.
在当前的全球环境下,疾病流行可能会迅速、轻易地蔓延到各个国家和大陆,对公众健康和世界经济造成破坏性影响。全球已有超过 5.13 亿人受到 SARS-CoV-2 感染,超过 620 万人因此死亡。大多数病毒都有治疗方法,但没有特效药。然而,通过在公共场所表面和个人防护设备(如口罩)上涂抹抗病毒涂层,可以限制病毒的传播。这项研究旨在制造一种以丙烯酸树脂为粘合剂的聚合物涂层,这种涂层对猫冠状病毒(FCov)具有很强的抗病毒活性。之所以选择聚乙二醇(PEG)作为抗病毒剂,是因为它具有 "绿色 "化学的优点,如无毒、廉价、易于回收、安全、天然、不易燃、生物相容性好和可生物降解。通过喷涂方法将不同重量百分比的 PEG/ 丙烯酸涂层体系涂覆在玻璃基底上,并在室温下固化 24 小时。所开发的 PEG/ 丙烯酸涂层体系含有 20 重量百分比的 PEG,与其他重量百分比的 PEG 相比,对 FCov 的抗病毒活性最高,达到 99.9%。从这项研究中可以看出,涂层的亲水性在抗病毒活性中起着重要作用。所开发的涂层具有亲水性,其接触角测量值为 83.28 ± 0.5°。傅立叶变换红外光谱(FTIR)显示,涂层样品中不含有任何现有的有毒成分或新成分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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