Comparison of Brain Natriuretic Peptide and Other Laboratory Parameters of Those Who Died From Coronavirus Disease and Those Who Were Discharged

Mehmet Özdi̇n, Mehmet Köroğlu, S. Yaylacı, E. Çokluk, İbrahim Kocayi̇ği̇t, Aziz Öğütlü
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Abstract

Objectıve: In this study, we aim to compare the brain natriuretic peptide (BNP) of patients who were diagnosed with COVID-19 infection, who were hospitalized and discharged, and those who died. Materials and Methods: The study was conducted on 474 patients diagnosed with COVID-19 disease. Information of 56 patients who died and 418 patients with COVID-19 who were discharged were obtained from the hospital information management system (HIMS) and analyzed retrospectively. The relationship between BNP, white blood cell (WBC), neutrophil (NEU), lymphocyte (LYM), platelet (PLT), Procalcitonin (PCT), High Sensitive Troponin I (hs Tn I), D-dimer and C-Reactive Protein (CRP) levels in deceased patients and discharged patients researched. Results: There was no statistically significant difference in mortality between women and men (p=0.385). There was no statistically significant difference in BNP, WBC, NEU, LYM, platelet, PCT and hs Tn I values between those who died and those who were discharged. D-dimer and CRP values of those who died and discharged were statistically significant (p< 0.031 and 0.020, respectively). Conclusions: Increased levels of CRP and D-dimer were found to be associated with mortality. More comprehensive studies are needed on this subject.
冠状病毒病死亡者与出院者脑钠肽及其他实验室参数的比较
目的本研究旨在比较确诊感染 COVID-19、住院、出院和死亡患者的脑钠肽 (BNP)。材料与方法:研究对象为 474 名确诊感染 COVID-19 的患者。从医院信息管理系统(HIMS)中获取了 56 名死亡患者和 418 名出院的 COVID-19 患者的信息,并进行了回顾性分析。研究了死亡患者和出院患者的 BNP、白细胞(WBC)、中性粒细胞(NEU)、淋巴细胞(LYM)、血小板(PLT)、降钙素原(PCT)、高敏肌钙蛋白 I(hs Tn I)、D-二聚体和 C-反应蛋白(CRP)水平之间的关系。结果女性和男性的死亡率差异无统计学意义(P=0.385)。死亡和出院患者的 BNP、WBC、NEU、LYM、血小板、PCT 和 hs Tn I 值差异无统计学意义。死亡者和出院者的 D-二聚体和 CRP 值有统计学意义(P< 0.031 和 0.020)。结论研究发现 CRP 和 D-二聚体水平的升高与死亡率有关。需要对这一问题进行更全面的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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