EXAMINATION OF NEUTROPHIL/LYMPHOCYTE (NLR), MONOCYTE/LYMPHOCYTE (MLR), AND PLATELET/LYMPHOCYTE (PLR) RATIOS BETWEEN ALZHEIMER'S DISEASE AND VASCULAR DEMENTIA

Taylan Yavuz Bulut, A. Şair
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Abstract

Background: The present study aims to investigate whether proinflammatory marker ratios in whole blood differ in these two dementia diseases. Materials and Methods: This study will involve Alzheimer's disease (AD) and vascular dementia (VaD) patients who were treated as outpatients in the outpatient clinic and inpatients in the ward of the Neurology Department of Adnan Menderes University Hospital. The patients’ diagnoses will be scanned in the hospital information system. The admission blood results of patients who presented between January 2018 and September 2020 will be included, and the patients’ hemogram results will be scanned retrospectively. Neutrophil/lymphocyte, monocyte/lymphocyte, and platelet/lymphocyte ratios in the hemogram results will be calculated and recorded. Results: In the AD-VaD comparison of the patients participating in the study, a significant difference was identified between the variability of platelet/lymphocyte (PLR) and NLRs (NLR) (p
中性粒细胞/淋巴细胞(nlr)、单核细胞/淋巴细胞(mlr)和血小板/淋巴细胞(plr)在阿尔茨海默病和血管性痴呆之间的比例研究
研究背景本研究旨在探讨这两种痴呆症患者全血中的促炎标记物比例是否存在差异。材料与方法:本研究将涉及阿尔茨海默病(AD)和血管性痴呆(VaD)患者,他们分别在阿德南-门德尔斯大学医院神经内科门诊和病房接受治疗。患者的诊断结果将在医院信息系统中进行扫描。将纳入 2018 年 1 月至 2020 年 9 月期间就诊患者的入院血液结果,并回顾性扫描患者的血液造影结果。计算并记录血象结果中的中性粒细胞/淋巴细胞比值、单核细胞/淋巴细胞比值、血小板/淋巴细胞比值。结果在对参与研究的患者进行 AD-VaD 对比时,发现血小板/淋巴细胞(PLR)和 NLR(NLR)的变异性之间存在显著差异(p
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