Follow up of serum ferritin levels in myocardial infarction in Indian males

Abstract

National health & nutritional examination survey, 1988-1994, first time reported a significant positive association in iron storage & heart disease risk. Due to the scarcity of this type of study in India, we did this study to find out the relation of serum ferritin with MIThe current study attempts to evaluation association of ferritin levels at the onset of AMI & at 6 day of follow up of subjects. A total of 39 male patients who were confirmed of having MI on the basis of lipid profile, CKMB, SGOT, SGPT, Trop I, ECG & Chest X Ray were included in the study. Serum ferritin level was estimated in study group on day 1 & day 6 of MI attack while only once in control. Serum ferritin was estimated by enzyme linked fluorescent assay on Mini Vidas auto analyzer from Biomerieux. Mean serum ferritin levels at Day-1 was not significantly elevated than controls [58.51 (±18.71) ng/ml in day-1 versus 64.09 (±19.42)]. In contrast serum ferritin levels at Day-6 were significantly elevated than controls [226.68 (±18.71) ng/ml at day-6 versus versus ferritin levels in controls (p < 0.001)]. : In conclusion, our data supports that elevated serum ferritin levels are associated with pathogenesis of AMI.