Blood Glucose Control on Diabetic Patient Type I using Sliding Mode Adaptive Control

Q2 Mathematics
Aminatus Sa'adah, Prihantini Prihantini
{"title":"Blood Glucose Control on Diabetic Patient Type I using Sliding Mode Adaptive Control","authors":"Aminatus Sa'adah, Prihantini Prihantini","doi":"10.5614/cbms.2023.6.2.1","DOIUrl":null,"url":null,"abstract":"Diabetes is a metabolic disorder due to insufficient insulin synthesis or inadequate insulin sensitivity. The Bergman’s minimal model describes the dynamics of blood glucose levels in type 1 diabetics. The model has control inputs in the form of insulin injections and covers external disturbance factors in the form of meal disturbances. This research developed a control design using an sliding mode adaptive control to reduce blood glucose levels in hyperglycemic patients and keep it within normal glucose levels. Sliding mode adaptive control is an adaptive controller updates the model based on measured performance while in operation. A numerical simulation of the proposed controller is carried out by giving eating disorders three times, namely at breakfast, lunch, and dinner. Based on the numerical simulation, to lower the high blood glucose in the hyperglicemic patient, the insulin injection should be given starting at 30 minutes before breakfast for the next four hour, with a maximal dose of injection is 13 mU/min. It can decrease the high blood pressure until 54.83%.","PeriodicalId":33129,"journal":{"name":"Communication in Biomathematical Sciences","volume":" 8","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Communication in Biomathematical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5614/cbms.2023.6.2.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Mathematics","Score":null,"Total":0}
引用次数: 0

Abstract

Diabetes is a metabolic disorder due to insufficient insulin synthesis or inadequate insulin sensitivity. The Bergman’s minimal model describes the dynamics of blood glucose levels in type 1 diabetics. The model has control inputs in the form of insulin injections and covers external disturbance factors in the form of meal disturbances. This research developed a control design using an sliding mode adaptive control to reduce blood glucose levels in hyperglycemic patients and keep it within normal glucose levels. Sliding mode adaptive control is an adaptive controller updates the model based on measured performance while in operation. A numerical simulation of the proposed controller is carried out by giving eating disorders three times, namely at breakfast, lunch, and dinner. Based on the numerical simulation, to lower the high blood glucose in the hyperglicemic patient, the insulin injection should be given starting at 30 minutes before breakfast for the next four hour, with a maximal dose of injection is 13 mU/min. It can decrease the high blood pressure until 54.83%.
使用滑动模式自适应控制对 I 型糖尿病患者进行血糖控制
糖尿病是一种由于胰岛素合成不足或胰岛素敏感性不足引起的代谢紊乱。伯格曼最小模型描述了 1 型糖尿病患者血糖水平的动态变化。该模型的控制输入为胰岛素注射,外部干扰因素为膳食干扰。这项研究开发了一种使用滑动模式自适应控制的控制设计,以降低高血糖患者的血糖水平,并将其控制在正常血糖水平内。滑动模式自适应控制是一种自适应控制器,可根据运行时的测量性能更新模型。通过在早餐、午餐和晚餐三次饮食失调,对所提出的控制器进行了数值模拟。根据数值模拟,要降低高血糖患者的高血糖,应从早餐前 30 分钟开始注射胰岛素,持续 4 个小时,最大注射剂量为 13 mU/分钟。它可以将高血压降低至 54.83%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Communication in Biomathematical Sciences
Communication in Biomathematical Sciences Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (miscellaneous)
CiteScore
3.60
自引率
0.00%
发文量
7
审稿时长
24 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信