Consensus on safety management of novel hormonal therapy for advanced prostate cancer

UroPrecision Pub Date : 2023-12-20 DOI:10.1002/uro2.22
Sujun Han, Shudong Cheng, Degang Ding, Jianming Guo, Zhisong He, Baiye Jin, Zhigang Ji, Tianxin Lin, Yuanjie Niu, Weijun Qin, Benkang Shi, Jinkai Shao, Xi'nan Sheng, Qiang Wei, Xin Wang, Xinghuan Wang, Shujie Xia, Wanhai Xu, Qing Zou, Xiongbing Zu, Renu Eapen, Chi‐Fai Ng, Hirotsugu Uemura, Hiroji Uemura, Cheol Kwak, Jae Young Joung, Marniza Saad, Edmund Chiong, Nianzeng Xing
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Abstract

Prostate cancer (PCa) is one of the most prevalent malignant tumors in men, accompanied by high incidence and mortality rates. Novel hormonal therapy (NHT) has emerged as the primary treatment for advanced PCa, providing noticeable clinical benefits. However, the diverse range of adverse events (AEs) associated with NHT may influence both treatment efficacy and patients' quality of life. In light of the latest international clinical research evidence and recommendations from domestic and foreign guidelines, this consensus aims to provide a comprehensive overview of the common AEs experienced during NHT for advanced PCa patients. Additionally, it seeks to develop a hierarchical approach to more efficiently manage AEs, presenting valuable insights for clinical medication and adverse reaction management.
晚期前列腺癌新型激素疗法的安全管理共识
前列腺癌(PCa)是男性最常见的恶性肿瘤之一,发病率和死亡率都很高。新型激素疗法(NHT)已成为晚期前列腺癌的主要治疗方法,并带来了显著的临床疗效。然而,与 NHT 相关的各种不良事件(AEs)可能会影响治疗效果和患者的生活质量。根据最新的国际临床研究证据和国内外指南的建议,本共识旨在全面概述晚期 PCa 患者在 NHT 治疗过程中出现的常见 AEs。此外,该共识还试图建立一种分级方法,以更有效地管理 AEs,为临床用药和不良反应管理提供有价值的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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