[Development of laser systems in the treatment of hyperpigmented skin lesions].

K Iwasaki, S Shimizu, M Osada, R Tanino, M Miyasaka, T Morita
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Abstract

Laser beams have been in common use for the treatment of hyperpigmented skin lesions. However, therapeutic efficacy has been limited mainly because the output is circular with a Gaussian distribution of intensity, which makes it difficult to apply a uniformly distributed dose to the lesions. We have developed a technique whereby a laser beam is converted to have a square and uniform output intensity distribution. The principle of this technique is that the divergent laser beam enters a glass square pillar, propagates through the pillar repeating the total reflection and emerges with a uniform intensity distribution over the cross-section at the end of the pillar. The device applied this technique is incorporated in a hand-piece and both ruby and argon laser systems have been developed. The ruby laser has been used for the treatment of the melanistic skin lesions such as nevus cell nevus and nevus spilus. In clinical application, 36 of 67 cases have shown remarkably effective results with an improvement rate of 53.7%. The argon laser has been used for the treatment of vasogenic skin lesions such as portwine stain. In clinical application, 44 of 66 cases have shown effective results and the improvement rate is 66.7%. These results are excellent when compared with the other methods of treatment and with laser therapy previously used.

激光系统在治疗色素沉着性皮肤病变中的发展
激光束已被普遍用于治疗色素沉着的皮肤病变。然而,治疗效果受到限制,主要是因为输出是圆形的,强度呈高斯分布,这使得很难将均匀分布的剂量应用于病变。我们已经开发了一种技术,该技术将激光束转换为具有正方形和均匀的输出强度分布。该技术的原理是,发散的激光束进入一个方形玻璃柱,通过重复全反射的柱传播,并以均匀的强度分布出现在柱端横截面上。应用这种技术的装置被集成在一个手板上,红宝石和氩气激光系统已经被开发出来。红宝石激光已被用于治疗黑色素皮肤病变,如痣细胞痣和痣外溢。在临床应用中,67例患者中有36例疗效显著,治愈率为53.7%。氩激光已被用于治疗血管源性皮肤病变,如portwine染色。在临床应用中,66例患者中有44例取得了有效效果,治愈率为66.7%。与其他治疗方法和以前使用的激光治疗相比,这些结果非常好。
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