Nanobody-mediated dualsteric engagement of the angiotensin receptor broadens biased ligand pharmacology

IF 3.2 3区医学 Q2 PHARMACOLOGY & PHARMACY

Molecular Pharmacology Pub Date : 2023-12-21 DOI:10.1124/molpharm.123.000797

Nayara Braga Emidio, Brandi M. Small, Amanda R. Keller, Ross W. Cheloha, L. Wingler

引用次数: 0

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纳米抗体介导的血管紧张素受体双steric参与拓宽了偏向配体的药理作用

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Pharmacology 医学-药学

CiteScore

7.20

自引率

2.80%

发文量

审稿时长

3-6 weeks

期刊介绍： Molecular Pharmacology publishes findings derived from the application of innovative structural biology, biochemistry, biophysics, physiology, genetics, and molecular biology to basic pharmacological problems that provide mechanistic insights that are broadly important for the fields of pharmacology and toxicology. Relevant topics include: Molecular Signaling / Mechanism of Drug Action Chemical Biology / Drug Discovery Structure of Drug-Receptor Complex Systems Analysis of Drug Action Drug Transport / Metabolism