Two Isomers of a Novel Ag(I) Complex with Pyrazole-Type Ligand—Synthesis, Structural, Thermal, and Antioxidative Characterization

IF 3.1 4区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR

Inorganics Pub Date : 2023-12-21 DOI:10.3390/inorganics12010004

Nikola D. Radnović, Nađa Štetin, M. Radanović, Ivana Đ. Borišev, M. Rodić, Ž. Jaćimović, Berta Barta Holló

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Abstract

The synthesis of the first Ag(I) complexes with ethyl-5-amino-1-methyl-1H-pyrazole-4-carboxylate (L) is presented. The reaction of AgClO4 with the ligand in a molar ratio of 1:1 gives a bis(ligand) complex [AgL2]ClO4 (1) in the presence of 4-formylbenzonitrile, monoperiodic polymer {[AgL2]ClO4}n (2). Characterization involved IR spectroscopy, conductometric measurements, thermogravimetric analysis, antioxidant tests, powder, and single crystal X-ray diffraction. Structural analysis revealed ligand coordination in a monodentate manner through the nitrogen atom of the pyrazole ring in both complexes. Complex 1 displayed a linear coordination environment for Ag(I), whereas, in complex 2, square-planar coordination was achieved with the additional involvement of two oxygen atoms from bridging perchlorate anions. Notably, the thermal properties of both isomers are found to be nearly identical. The significant antioxidant activity of the isomer with a reverse-oriented pyrazole-type ligand suggests its potential relevance in biological studies.

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带有吡唑类配体的新型 Ag(I) 复合物的两种异构体--合成、结构、热和抗氧化表征

本文介绍了首批 Ag(I) 与 5-氨基-1-甲基-1H-吡唑-4-羧酸乙酯（L）配合物的合成。AgClO4 与配体的摩尔比为 1:1，在 4-甲酰基苯甲腈存在下反应生成双（配体）络合物 [AgL2]ClO4（1），单周期聚合物 {[AgL2]ClO4}n （2）。表征包括红外光谱、电导测量、热重分析、抗氧化测试、粉末和单晶 X 射线衍射。结构分析表明，在这两种配合物中，配体通过吡唑环的氮原子以单配位方式配位。络合物 1 显示了 Ag(I) 的线性配位环境，而在络合物 2 中，由于桥接高氯酸盐阴离子的两个氧原子的额外参与，实现了方形配位。值得注意的是，这两种异构体的热特性几乎相同。带有反向吡唑配体的异构体具有明显的抗氧化活性，这表明它在生物研究中具有潜在的相关性。

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来源期刊

Inorganics Chemistry-Inorganic Chemistry

CiteScore

2.80

自引率

10.30%

发文量

193

审稿时长

6 weeks

期刊介绍： Inorganics is an open access journal that covers all aspects of inorganic chemistry research. Topics include but are not limited to: synthesis and characterization of inorganic compounds, complexes and materials structure and bonding in inorganic molecular and solid state compounds spectroscopic, magnetic, physical and chemical properties of inorganic compounds chemical reactivity, physical properties and applications of inorganic compounds and materials mechanisms of inorganic reactions organometallic compounds inorganic cluster chemistry heterogenous and homogeneous catalytic reactions promoted by inorganic compounds thermodynamics and kinetics of significant new and known inorganic compounds supramolecular systems and coordination polymers bio-inorganic chemistry and applications of inorganic compounds in biological systems and medicine environmental and sustainable energy applications of inorganic compounds and materials MD