Fetal bovine acellular dermal matrix in the management of chronic nonhealing lower extremity wounds.

IF 1 4区医学 Q4 DERMATOLOGY

Wound management & prevention Pub Date : 2023-11-01 DOI:10.25270/wmp.23031

Susan Benitez-Sanchez, Amit Rao, Alisha Oropallo

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Abstract

Background: The management of chronic nonhealing lower extremity wounds remains a problem that substantially affects patients and significantly burdens the health care system. Nonhealing wounds lead to increased hospitalization, decreased quality of life, minor and major amputations, and increased risk of mortality. Dermal matrices have advanced the science of wound healing.

Purpose: To evaluate fetal bovine acellular dermal matrix (FBADM), an acellular dermal collagen repair scaffold derived from fetal bovine dermis, in the management of chronic nonhealing lower extremity wounds.

Methods: A single-center retrospective chart review was conducted to collect data on patients with chronic nonhealing lower extremity wounds treated with FBADM from January 2013 through December 2019.

Results: A total of 43 patients were enrolled, with a mean age of 68.5 years and a mean wound area of 27 cm2. Complete closure of the wound occurred in 53% of patients overall, with 28% of patients achieving healing within 12 weeks.

Conclusion: Application of FBADM in the management of chronic nonhealing lower extremity wounds is safe, effective, and efficient.

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胎牛非细胞真皮基质在治疗慢性下肢不愈合伤口中的应用。

背景：慢性下肢伤口不愈合的管理仍然是一个严重影响患者和加重医疗保健系统负担的问题。伤口不愈合会导致住院时间增加、生活质量下降、轻度和重度截肢以及死亡风险增加。目的：评估胎牛无细胞真皮基质（FBADM）--一种从胎牛真皮中提取的无细胞真皮胶原修复支架--在治疗慢性下肢不愈合伤口中的应用：方法：对2013年1月至2019年12月期间使用FBADM治疗慢性下肢不愈合伤口的患者数据进行了单中心回顾性病历审查：共有 43 名患者入选，平均年龄为 68.5 岁，平均伤口面积为 27 平方厘米。53%的患者伤口完全闭合，28%的患者伤口在12周内愈合：结论：应用 FBADM 治疗慢性下肢不愈合伤口是安全、有效和高效的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Wound management & prevention Nursing-Medical and Surgical Nursing

CiteScore

1.70

自引率

8.30%

发文量

期刊介绍： Information not localized