[Treatment regimen for deep sternal wound infections after cardiac surgical interventions in an interdisciplinary approach].

Unfallchirurgie (Heidelberg, Germany) Pub Date : 2024-03-01 Epub Date: 2023-12-12 DOI:10.1007/s00113-023-01394-x
D Bieler, A Franke, M Völlmecke, S Hentsch, A Markewitz, E Kollig
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Abstract

The aim of this article is to present the importance of a structured and situation-adapted approach based on the diagnostic and therapeutic strategy in the interdisciplinary treatment of 54 patients with deep sternal wound infections (DSWI) after cardiac surgical interventions and the results achieved. The patients were 41 men and 13 women with an average age of 65.1 years, who developed a DSWI after a cardiac surgical intervention during the period 2003-2016. The treatment strategy included a thorough debridement including the removal of indwelling foreign material, the reconstruction with a stable re-osteosynthesis after overcoming the infection and if necessary, situation-related surgical flaps for a defect coverage with a good blood supply and mandatory avoidance of dead spaces. A total of 146 operations were necessary (average 2.7 operations/patient, range 1-7 operations). In 24.1 % of the cases a one-stage approach could be carried out. In 41 patients negative pressure wound therapy (NPWT) with programmed sponge changing was used for wound conditioning (mean 5 changes, standard deviation, SD± 5.6 changes over 22 days, SD± 23.9 days, change interval every 3-4 days in 40.7% of the cases). In 33 patients a bilateral myocutaneous pectoralis major flap was used, in 4 patients a vertical rectus abdominis myocutaneous (VRAM) flap and in 7 patients both were carried out. A total of 43 osteosynthesis procedures were carried out on the sternum with fixed-angle titanium plates. Of the patients 7 died during intensive care unit treatment (total mortality 13 %, n = 5, 9.3 % ≤ 30 days) or in the later course. Of the patients 47 (87.1 %) could be discharged with a cleansed infection. In 2 patients the implant was removed after 2 years due to loosening.

[心脏外科手术后胸骨深部伤口感染的跨学科治疗方案]。
本文旨在介绍基于诊断和治疗策略的结构化和适应情况的方法在跨学科治疗 54 例心脏外科手术后胸骨深部伤口感染(DSWI)患者中的重要性以及取得的效果。这些患者中有 41 名男性和 13 名女性,平均年龄为 65.1 岁,都是在 2003-2016 年期间接受心脏手术治疗后出现胸骨深部伤口感染的。治疗策略包括彻底清创,包括清除留置的异物,在克服感染后使用稳定的再骨合成物进行重建,必要时使用与情况相关的手术皮瓣,以良好的血液供应覆盖缺损,并强制避免死腔。总共需要进行 146 次手术(平均每名患者 2.7 次,1-7 次不等)。24.1%的病例可以采用一步法。在 41 例患者中,采用了负压伤口疗法(NPWT)和程序化海绵更换来调节伤口(平均更换 5 次,标准差,SD± 5.6 次,历时 22 天,SD± 23.9 天,40.7% 的病例每 3-4 天更换一次)。33例患者使用了双侧胸大肌皮瓣,4例患者使用了垂直腹直肌肌皮瓣(VRAM),7例患者同时使用了两种皮瓣。共使用固定角度的钛板对胸骨进行了 43 次骨合成手术。其中7名患者在重症监护室治疗期间(总死亡率13%,n=5,9.3% ≤ 30天)或在后期治疗过程中死亡。47名患者(87.1%)在感染消除后出院。2 名患者在 2 年后因松动而取出了植入物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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