Exploratory assessment of right ventricular structure and function during prolonged endurance cycling exercise.

IF 3.2 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Echo Research and Practice Pub Date : 2023-12-20 DOI:10.1186/s44156-023-00035-8

Rachel N Lord, Zoe H Adams, Keith George, John Somauroo, Helen Jones, David Oxborough

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引用次数: 0

Abstract

Background: A reduction in right ventricular (RV) function during recovery from prolonged endurance exercise has been documented alongside RV dilatation. A relative elevation in pulmonary artery pressure and therefore RV afterload during exercise has been implicated in this post-exercise dysfunction but has not yet been demonstrated. The current study aimed to assess RV structure and function and pulmonary artery pressure before, during and after a 6-h cycling exercise bout.

Methods: Eight ultra-endurance athletes were recruited for this study. Participants were assessed prior to exercise supine and seated, during exercise at 2, 4 and 6 h whilst cycling seated at 75% maximum heart rate, and post-exercise in the supine position. Standard 2D, Doppler and speckle tracking echocardiography were used to determine indices of RV size, systolic and diastolic function.

Results: Heart rate and RV functional parameters increased from baseline during exercise, however RV structural parameters and indices of RV systolic and diastolic function were unchanged between in-exercise assessment points. Neither pulmonary artery pressures (26 ± 9 mmHg vs 17 ± 10 mmHg, P > 0.05) nor RV wall stress (7.1 ± 3.0 vs 6.2 ± 2.4, P > 0.05) were significantly elevated during exercise. Despite this, post-exercise measurements revealed RV dilation (increased RVD1 and 3), and reduced RV global strain (- 21.2 ± 3.5 vs - 23.8 ± 2.3, P = 0.0168) and diastolic tissue velocity (13.8 ± 2.5 vs 17.1 ± 3.4, P = 0.019) vs pre-exercise values.

Conclusion: A 6 h cycling exercise bout at 75% maximum heart rate did not alter RV structure, systolic or diastolic function assessments during exercise. Pulmonary artery pressures are not elevated beyond normal limits and therefore RV afterload is unchanged throughout exercise. Despite this, there is some evidence of RV dilation and altered function in post-exercise measurements.

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探索性评估长时间耐力自行车运动时的右心室结构和功能。

背景：有记录显示，在长时间耐力运动后的恢复过程中，右心室（RV）功能下降，同时 RV 扩张。肺动脉压力的相对升高以及运动时 RV 后负荷被认为与运动后功能障碍有关，但尚未得到证实。本研究旨在评估 6 小时自行车运动前、运动中和运动后的 RV 结构和功能以及肺动脉压力：方法：本研究招募了八名超耐力运动员。方法：本研究招募了 8 名超耐力运动员，分别在运动前仰卧和坐姿、运动中 2、4 和 6 小时（以 75% 的最大心率骑行）以及运动后仰卧位进行评估。采用标准二维、多普勒和斑点追踪超声心动图确定 RV 大小、收缩和舒张功能指数：结果：运动时心率和 RV 功能参数较基线有所上升，但 RV 结构参数以及 RV 收缩和舒张功能指数在运动中评估点之间没有变化。运动时肺动脉压（26 ± 9 mmHg vs 17 ± 10 mmHg，P > 0.05）和 RV 壁应力（7.1 ± 3.0 vs 6.2 ± 2.4，P > 0.05）均无明显升高。尽管如此，运动后的测量显示 RV 扩张（RVD1 和 3 增加），RV 整体应变（- 21.2 ± 3.5 vs - 23.8 ± 2.3，P = 0.0168）和舒张组织速度（13.8 ± 2.5 vs 17.1 ± 3.4，P = 0.019）与运动前的值相比有所降低：结论：在最大心率为 75% 的情况下进行 6 小时的骑车运动不会改变运动时的 RV 结构、收缩或舒张功能评估。肺动脉压力的升高没有超出正常范围，因此在整个运动过程中 RV 后负荷保持不变。尽管如此，在运动后的测量中仍有一些证据表明 RV 扩张和功能改变。

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来源期刊

Echo Research and Practice CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

6.70

自引率

12.70%

发文量

审稿时长

8 weeks

期刊介绍： Echo Research and Practice aims to be the premier international journal for physicians, sonographers, nurses and other allied health professionals practising echocardiography and other cardiac imaging modalities. This open-access journal publishes quality clinical and basic research, reviews, videos, education materials and selected high-interest case reports and videos across all echocardiography modalities and disciplines, including paediatrics, anaesthetics, general practice, acute medicine and intensive care. Multi-modality studies primarily featuring the use of cardiac ultrasound in clinical practice, in association with Cardiac Computed Tomography, Cardiovascular Magnetic Resonance or Nuclear Cardiology are of interest. Topics include, but are not limited to: 2D echocardiography 3D echocardiography Comparative imaging techniques – CCT, CMR and Nuclear Cardiology Congenital heart disease, including foetal echocardiography Contrast echocardiography Critical care echocardiography Deformation imaging Doppler echocardiography Interventional echocardiography Intracardiac echocardiography Intraoperative echocardiography Prosthetic valves Stress echocardiography Technical innovations Transoesophageal echocardiography Valve disease.