Insulin initiation in patients with type 2 diabetes is often delayed, but access to a diabetes nurse may help-insights from Norwegian general practice.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-03-01 Epub Date: 2024-02-07 DOI:10.1080/02813432.2023.2296118
Ibrahimu Mdala, Kjersti Nøkleby, Tore Julsrud Berg, John Cooper, Sverre Sandberg, Karianne Fjeld Løvaas, Tor Claudi, Anne Karen Jenum, Esben Selmer Buhl
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Abstract

Objective: We opted to study how support staff operational capacity and diabetes competences may impact the timeliness of basal insulin-initiation in general practice patients with type 2 diabetes (T2D).Design/Setting/Outcomes: This was an observational and retrospective study on Norwegian primary care patients with T2D included from the ROSA4-dataset. Exposures were (1) support staff size, (2) staff size relative to number of GPs, (3) clinic access to a diabetes nurse and (4) share of staff with diabetes course (1 and 2 both relate to staff operational capacity, whereas 3 and 4 are both indicatory of staff diabetes competences). Outcomes were 'timely basal insulin-initiation' (primary) and 'attainment of HbA1c<7%' after insulin start-up (secondary). Associations were analyzed using multiple linear regression, and directed acyclic graphs guided statistical adjustments.Subjects: Insulin naïve patients with 'timely' (N = 294), 'postponed' (N = 219) or 'no need of' (N = 3,781) basal insulin-initiation, respectively.Results: HbA1c [median (IQR)] increased to 8.8% (IQR, 8.0, 10.2) prior to basal insulin-initiation, which reduced HbA1c to 7.3 (6.8-8.1) % by which only 35% of the subjects reached HbA1c <7%. Adjusted risk of 'timely basal insulin-initiation' was more than twofold higher if access to a diabetes nurse (OR = 2.40, [95%CI, 1.68, 3.43]), but related only vaguely to staff size (OR = 1.01, [95%CI, 1.00, 1.03]). No other staff factors related significantly to neither the primary nor the secondary outcome.Conclusion: In Norwegian general practice, insulin initiation in people with T2D may be affected by therapeutic inertia but access to a diabetes nurse may help facilitating more timely insulin start-up.

2型糖尿病患者开始使用胰岛素的时间往往被推迟,但获得糖尿病护士的帮助可能会有所帮助--挪威全科医生的见解。
目的:我们选择研究辅助人员的业务能力和糖尿病能力如何影响全科2型糖尿病(T2D)患者启动基础胰岛素的及时性:这是一项观察性和回顾性研究,研究对象是ROSA4数据集中的挪威全科2型糖尿病患者。暴露因素包括:(1)辅助人员的规模;(2)人员规模与全科医生人数的相对比例;(3)糖尿病护士的门诊就诊率;(4)接受过糖尿病课程培训的人员比例(1和2均与人员的业务能力有关,而3和4则表明人员的糖尿病能力)。结果是 "及时启动基础胰岛素"(主要)和 "达到 HbA1cSubjects":分别为 "及时"(294 人)、"推迟"(219 人)或 "无需"(3781 人)启动基础胰岛素治疗的胰岛素新患者:结果:在开始使用基础胰岛素之前,HbA1c[中位数(IQR)]升至8.8%(IQR,8.0,10.2),而在开始使用基础胰岛素之后,HbA1c降至7.3%(6.8-8.1),只有35%的受试者达到了HbA1c结论:在挪威全科诊所,T2D患者开始使用胰岛素可能会受到治疗惰性的影响,但糖尿病护士的参与可能有助于更及时地开始使用胰岛素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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