Oncolytic viruses in lung cancer treatment: a review article.

IF 2.7 4区医学 Q3 IMMUNOLOGY

Immunotherapy Pub Date : 2024-02-01 Epub Date: 2023-12-19 DOI:10.2217/imt-2023-0124

Hanie Sakhi, Mohadeseh Arabi, Amir Ghaemi, Abolfazl Movafagh, Mojgan Sheikhpour

引用次数: 0

Abstract

Lung cancer has a high morbidity rate worldwide due to its resistance to therapy. So new treatment options are needed to improve the outcomes of lung cancer treatment. This study aimed to evaluate the effectiveness of oncolytic viruses (OVs) as a new type of cancer treatment. In this study, 158 articles from PubMed and Scopus from 1994 to 2022 were reviewed on the effectiveness of OVs in the treatment of lung cancer. The oncolytic properties of eight categories of OVs and their interactions with treatment options were investigated. OVs can be applied as a promising immunotherapy option, as they are reproduced selectively in different types of cancer cells, cause tumor cell lysis and trigger efficient immune responses.

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肺癌治疗中的溶瘤病毒：综述文章。

肺癌在全世界的发病率都很高，因为它对治疗具有抗药性。因此，需要新的治疗方案来改善肺癌的治疗效果。本研究旨在评估溶瘤病毒（OV）作为一种新型癌症治疗方法的有效性。本研究回顾了1994年至2022年期间PubMed和Scopus上158篇关于OVs治疗肺癌有效性的文章。研究调查了八类OV的溶瘤特性及其与治疗方案的相互作用。OVs可作为一种有前景的免疫疗法，因为它们可选择性地在不同类型的癌细胞中繁殖，导致肿瘤细胞溶解，并引发有效的免疫反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Immunotherapy 医学-免疫学

CiteScore

5.00

自引率

3.60%

发文量

113

审稿时长

6-12 weeks

期刊介绍： Many aspects of the immune system and mechanisms of immunomodulatory therapies remain to be elucidated in order to exploit fully the emerging opportunities. Those involved in the research and clinical applications of immunotherapy are challenged by the huge and intricate volumes of knowledge arising from this fast-evolving field. The journal Immunotherapy offers the scientific community an interdisciplinary forum, providing them with information on the most recent advances of various aspects of immunotherapies, in a concise format to aid navigation of this complex field. Immunotherapy delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this vitally important area of research. Unsolicited article proposals are welcomed and authors are required to comply fully with the journal''s Disclosure & Conflict of Interest Policy as well as major publishing guidelines, including ICMJE and GPP3.