Effect of transversus abdominis plane block with or without buprenorphine after inguinal hernia surgery on postoperative pain.

IF 1.6 Q2 ANESTHESIOLOGY
Nirvana Ahmed Elshalakany, Asmaa Mohamed Salah
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Abstract

Introduction: Transversus abdominis plane (TAP) has been mentioned as having bene-ficial effects on chronic pain after hernioplasty. This study assessed the effects of TAP block on acute and persistent postoperative pain after inguinal hernia surgery, with or without buprenorphine.

Material and methods: 64 patients were allocated to group R ( n = 32) and received 20 mL of 0.25% ropivacaine for TAP block; group RB ( n = 32) received 20 mL of 0.25% ropivacaine containing 300 µg of buprenorphine for TAP block. The primary outcome was the analgesic and antihyperalgesic effect of buprenorphine. The duration of analgesia, analgesic consumption, postoperative pain scores at rest and sitting up to 48 hours, and the effect on wound hyperalgesia were evaluated. Secondary outcomes included the incidence of side effects and complications.

Results: The median (IQR) duration of analgesia in group R was 386.5 (37.25) minutes vs. 868 (41.3) minutes in the RB group. Median pain scores on sitting were found to be significantly better in group RB than in group R at 6, 12, and 24 hours ( P < 0.001). The wound hyperalgesia index showed a significant difference between groups ( P < 0.001). The incidence of persistent postoperative pain was 6.25% in the R group, as compared to 0% in the RB group. Otherwise, the patients did not have any further complications associated with the block.

Conclusions: The results demonstrated that TAP block with buprenorphine reduced acute postoperative pain severity, but we did not find a difference between groups in persistent pain.

腹股沟疝气手术后使用或不使用丁丙诺啡进行腹横肌平面阻滞对术后疼痛的影响。
简介有人提到腹横肌平面(TAP)对疝气成形术后的慢性疼痛有好处。本研究评估了 TAP 阻滞对腹股沟疝手术后急性和持续性术后疼痛的影响,无论是否使用丁丙诺啡。材料和方法:64 名患者被分配到 R 组(32 人),接受 20 mL 0.25% 罗哌卡因进行 TAP 阻滞;RB 组(32 人)接受 20 mL 含有 300 µg 丁丙诺啡的 0.25% 罗哌卡因进行 TAP 阻滞。主要结果是丁丙诺啡的镇痛和抗过敏作用。评估内容包括镇痛持续时间、镇痛剂消耗量、术后休息和坐位 48 小时内的疼痛评分以及对伤口痛觉减退的影响。次要结果包括副作用和并发症的发生率:结果:R组镇痛持续时间的中位数(IQR)为386.5(37.25)分钟,而RB组为868(41.3)分钟。在 6、12 和 24 小时内,RB 组坐位疼痛评分的中位数明显优于 R 组(P < 0.001)。伤口痛觉减退指数在各组之间存在显著差异(P < 0.001)。R 组术后持续疼痛的发生率为 6.25%,而 RB 组为 0%。除此之外,患者没有再出现任何与阻滞相关的并发症:结果表明,使用丁丙诺啡进行 TAP 阻滞可降低术后急性疼痛的严重程度,但我们并未发现各组间在持续性疼痛方面存在差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.00
自引率
5.90%
发文量
48
审稿时长
25 weeks
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