How much schizophrenia do famines cause?

IF 8.3 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces Pub Date : 2023-12-19 DOI:10.1038/s41537-023-00416-2

Cormac Ó Gráda, Chihua Li, L. H. Lumey

引用次数: 0

Abstract

Since the 1970s, famines have been widely invoked as natural experiments in research into the long-term impact of foetal exposure to nutritional shocks. That research has produced compelling evidence for a robust link between foetal exposure and the odds of developing schizophrenia. However, the implications of that research for the human cost of famines in the longer run have not been investigated. We address the connection between foetal origins and schizophrenia with that question in mind. The impact turns out to be very modest—much less than one per cent of the associated famine death tolls—across a selection of case studies.

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饥荒会导致多少精神分裂症？

自 20 世纪 70 年代以来，在研究胎儿受到营养冲击的长期影响时，人们广泛援引饥荒作为自然实验。这项研究提出了令人信服的证据，证明胎儿受到营养冲击与患精神分裂症的几率之间存在密切联系。然而，这项研究对饥荒对人类造成的长期代价的影响却没有进行调查。带着这个问题，我们探讨了胎儿来源与精神分裂症之间的联系。结果表明，在所选择的案例研究中，这种影响非常小--远远小于相关饥荒死亡人数的百分之一。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Materials & Interfaces 工程技术-材料科学：综合

CiteScore

16.00

自引率

6.30%

发文量

4978

审稿时长

1.8 months

期刊介绍： ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.