{"title":"The Multivariate Generalized Linear Hawkes Process in High Dimensions with Applications in Neuroscience","authors":"Masoumeh Fallahi, Reza Pourtaheri, Farzad Eskandari","doi":"10.1007/s11009-023-10063-w","DOIUrl":null,"url":null,"abstract":"<p>The Hawkes process models have been recently become a popular tool for modeling and analysis of neural spike trains. In this article, motivated by neuronal spike trains study, we propose a novel multivariate generalized linear Hawkes process model, where covariates are included in the intensity function. We consider the problem of simultaneous variable selection and estimation for the multivariate generalized linear Hawkes process in the high-dimensional regime. Estimation of the intensity function of the high-dimensional point process is considered within a nonparametric framework, applying B-splines and the SCAD penalty for matters of sparsity. We apply the Doob-Kolmogorov inequality and the martingale central limit theory to establish the consistency and asymptotic normality of the resulting estimators. Finally, we illustrate the performance of our proposal through simulation and demonstrate its utility by applying it to the neuron spike train data set.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1007/s11009-023-10063-w","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The Hawkes process models have been recently become a popular tool for modeling and analysis of neural spike trains. In this article, motivated by neuronal spike trains study, we propose a novel multivariate generalized linear Hawkes process model, where covariates are included in the intensity function. We consider the problem of simultaneous variable selection and estimation for the multivariate generalized linear Hawkes process in the high-dimensional regime. Estimation of the intensity function of the high-dimensional point process is considered within a nonparametric framework, applying B-splines and the SCAD penalty for matters of sparsity. We apply the Doob-Kolmogorov inequality and the martingale central limit theory to establish the consistency and asymptotic normality of the resulting estimators. Finally, we illustrate the performance of our proposal through simulation and demonstrate its utility by applying it to the neuron spike train data set.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.