Design of small molecules for CDK-2 inhibition in colorectal cancer based on substructure search

Journal of Biomolecular Structure and Dynamics Pub Date : 2023-12-13 DOI:10.1080/07391102.2023.2291546

Uchechukwu C. Ogbodo, Sofela Salimat, Damilola S. Bodun, Toheeb A. Balogun, Damilola A. Omoboyowa

引用次数: 0

Abstract

The global frequency of colorectal cancer motivates extensive drug discovery efforts. CDK2, a key member of the CDK family, has been linked to tumor progression, unregulated cell proliferation, and...

查看原文本刊更多论文

基于子结构搜索设计抑制结直肠癌 CDK-2 的小分子化合物

结直肠癌的全球频率促使了广泛的药物发现工作。CDK2是CDK家族的关键成员，与肿瘤进展、不受调节的细胞增殖和…

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Biomolecular Structure and Dynamics

自引率

0.00%

发文量