Gardner's Syndrome—A Case Report and Brief Literature

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL
Mukul Shetty, Shrivya Saloni Mahaveeran, Arathi K., Akhil Shetty
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Abstract

Abstract Gardner's syndrome has been recognized as a hereditary affliction that is autosomal in nature. This disorder is known to exhibit characteristics of familial adenomatous polyposis, of which it is also considered a variation. The features of this syndrome include the gradual development of osteomas and epidermoid cysts, including a characteristic feature that is the noted presence of intestinal polyps, which are generally multiple in number. Additionally, dental anomalies have been observed and recorded in a sizeable ratio of cases encompassing an increased frequency of multiple odontomas that are benign tumors linked to the development of a tooth and tooth agenesis/hypodontia that refers to developmental absence of one or more teeth. The other dental ascertainment includes abnormal morphology of the tooth/teeth as well as the presence of supernumerary teeth and impacted or unerupted teeth. This case report outlines the case of a 59-year-old male patient who had reported to the clinic, and was then diagnosed with Gardner's syndrome post a thorough examination. On radiographic examination, the manifestation of multiple osteomas in the frontal bone was revealed. The presence of a motley of diffused benign lesions of the bone in both the upper and lower jaw as well as the presence of an epidermoid cyst on the scalp was suggestive of an exemplar presentation of Gardner's syndrome.
加德纳综合征--病例报告和文献简介
加德纳氏综合征被认为是一种常染色体遗传病。这种疾病已知表现出家族性腺瘤性息肉病的特征,它也被认为是一种变异。该综合征的特征包括骨瘤和表皮样囊肿的逐渐发展,其中一个特征是肠息肉的存在,通常是多个。此外,在相当大比例的病例中,已经观察到并记录了牙齿异常,其中包括与牙齿发育有关的多发性牙瘤和牙齿发育不全/牙齿缺损(指一颗或多颗牙齿发育缺失)的频率增加。其他牙齿鉴定包括牙齿形态异常、是否有多余牙齿、是否有阻生或未长出牙齿。本病例报告概述了一名59岁男性患者的病例,他曾到诊所报告,然后在彻底检查后被诊断为加德纳综合征。在x线检查中,显示了额骨多发骨瘤的表现。上颚和下颚骨的弥漫性良性病变以及头皮表皮样囊肿的出现提示加德纳综合征的典型表现。
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来源期刊
Journal of Health and Allied Sciences NU
Journal of Health and Allied Sciences NU MEDICINE, GENERAL & INTERNAL-
自引率
33.30%
发文量
85
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