Prognostic Factors for the Occurrence of Recurrent Major Adverse Cardiac Events after Isolated Coronary Arterial Bypass Graft

Hendyono Lim, Azzahra Maheswari Noersamsjah, Andry Irawan
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Abstract

Background: Coronary heart disease (CHD), commonly known as coronary artery disease (CAD), is a heart disorder that occurs when the arteries supplying blood to the heart walls experience hardening and narrowing, leading to a reduced supply of oxygen and nutrients to the myocardial tissue due to limited coronary blood flow. The treatment of CHD requires revascularization or reperfusion procedures on the coronary blood vessels responsible for supplying the heart muscle. One recommended therapy is coronary artery bypass grafting (CABG). Patients post-CABG are at risk of experiencing major adverse cardiovascular events (MACE). Methods: This design is a cross-sectional study involving all patients who underwent CABG at Siloam Hospitals in Lippo Village and Kebon Jeruk from January to June 2023. Data analysis using a regression approach aims to evaluate the relationship between various prognostic factors and MACE occurrences, thereby identifying a cross-sectional association between these variables and MACE events. Results: Findings from this cross-sectional study indicate a correlation between overweight and the occurrence of recurrent MACE in patients with a history of CABG (p-value = 0.037). These results suggest that individuals with obesity undergoing CABG have a higher risk of experiencing recurrent MACE in CHD. Conclusion: The prognostic factor for recurrent CHD-related major adverse cardiovascular events (MACE) is body mass index (BMI). Monitoring body mass index (BMI) in CHD patients who have undergone CABG is essential to reduce the risk of recurring MACE in the future.
孤立冠状动脉旁路移植术后复发重大心脏不良事件的预后因素
背景:冠心病(CHD),俗称冠状动脉疾病(CAD),是一种心脏疾病,当向心脏壁供血的动脉硬化和狭窄时发生,导致由于冠状动脉血流受限导致心肌组织的氧气和营养供应减少。冠心病的治疗需要对负责供应心肌的冠状血管进行血运重建或再灌注手术。一种推荐的治疗是冠状动脉旁路移植术(CABG)。冠脉搭桥后患者有发生重大心血管不良事件(MACE)的风险。方法:本设计是一项横断面研究,涉及2023年1月至6月在力宝村和Kebon Jeruk的西罗亚医院接受CABG手术的所有患者。使用回归方法的数据分析旨在评估各种预后因素与MACE发生之间的关系,从而确定这些变量与MACE事件之间的横断面关联。结果:横断面研究结果表明,有CABG病史的患者体重过重与MACE复发之间存在相关性(p值= 0.037)。这些结果表明,接受冠状动脉搭桥的肥胖患者在冠心病中复发MACE的风险更高。结论:体重指数(BMI)是复发性冠心病相关主要心血管不良事件(MACE)的预后因素。监测冠心病冠脉搭桥患者的身体质量指数(BMI)对于降低未来MACE复发的风险至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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