Development of allergy to LTP in children and adults

PhD M.Z. Lisiecka
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Abstract

Background. The importance of issue is the rising incidence of allergies to volatile organic compounds, particularly in children and adults. This necessitates understanding the causes, risk factors, and methods for prevention and treatment. The purpose of the study was to clarify the relationship between the development of allergy to lipid transfer proteins (LTP) and various environmental influences, nutrition and the immune state of the body. Materials and methods. To achieve goal, the following research methods were used: content analysis of the database of medical organizations, the method of a representative sample and quantitative examination. In the practical part of the study, we used the Immuno Solid-phase Allergen Chip test. Results. The study results demonstrated adverse reactions in both children and adults with LTP allergies. Peach (Prunus persica) was identified as an allergenic product. It was found that childhood is a particularly sensitive period for the development of allergic reactions to LTP due to incomplete immune development. Additionally, the peculiarities of food allergy were investigated, taking into account its connection with antibodies and cause-and-effect relationships. Conclusions. Sensitization to lipid transfer proteins occurs in various groups, including children and adults, and depends on the sources of exposure.
儿童和成人对 LTP 过敏的发展情况
背景。问题的重要性在于对挥发性有机化合物的过敏发生率不断上升,尤其是在儿童和成人中。这就需要了解病因、危险因素以及预防和治疗的方法。本研究的目的是阐明脂质转移蛋白(LTP)过敏的发展与各种环境影响、营养和机体免疫状态之间的关系。材料和方法。为了达到研究目的,采用了以下研究方法:对医疗机构数据库进行内容分析、代表性样本法和定量检验法。在研究的实践部分,我们使用了Immuno固相过敏原芯片测试。结果。研究结果表明,LTP过敏的儿童和成人均有不良反应。桃(Prunus persica)被确定为致敏产品。研究发现,由于免疫发育不完全,儿童时期是对LTP过敏反应发展的特别敏感时期。此外,研究了食物过敏的特点,考虑到它与抗体的联系和因果关系。结论。脂质转移蛋白致敏发生在各种人群中,包括儿童和成人,并取决于接触源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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