Hemoperfusion effect on oxygen-carrying function of preserved donor blood and erythrocytic mass.

Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR Pub Date : 1989-01-01

Khodas MYa, A L Belkin, L A Mosolova, M S Povzhitkova, S F Leonova, K A Penkrak, M N Grischenko, G K Pyatnitskaya

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Abstract

The purpose of the study was to explore the preserved (7-21 days) donor blood and erythrocytic mass, following perfusion through hemosorbent SKN-D. After the sorption the oxygen-transport function of erythrocytes was found to improve considerably (oxyhemoglobin dissociation curve was shifted to the right on average by 4-4.2 mm Hg). The energy supply became better (ATP level was increased by 38-59%). In view of the above, long-preserved blood and erythrocytic mass following their perfusion through SKN-D hemosorbent can be considered a sufficiently valid transfusion medium.

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血液灌流对保存供血及红细胞团块携氧功能的影响。

本研究的目的是探讨通过吸附剂SKN-D灌注后保存(7-21天)的供体血液和红细胞团块。吸附后红细胞的氧转运功能明显改善(血红蛋白氧解离曲线平均右移4-4.2 mm Hg)。能量供应好转(ATP水平提高38 ~ 59%)。综上所述，经SKN-D吸附剂灌注后长期保存的血液和红细胞团块可以被认为是足够有效的输血介质。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR

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