Social Vulnerability and Childhood Health: Bayesian Spatial Models to Assess Risks from Multiple Stressors on Childhood Diarrhoea in Malawi

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Lawrence N. Kazembe
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Abstract

Childhood diarrhoea accounts for over 15% of all under-five deaths in Africa. The disease is exacerbated by social vulnerability. This study operationalizes social vulnerability by using three indicators: water poverty, sanitation and assets, to capture social disadvantage, which measures individual or community resources to prevent or mitigate health effects. We particularly investigated the relationship between childhood diarrhoea and risks emanating from multiple stressors: water poverty, poor sanitation and low wealth status, which define social vulnerability. Using data from the 2013/14 Malawi MDG Endline Survey (MMES), we fitted spatial models assuming that the combined effect of social vulnerability indicators, together with individual covariates, exhibit spatial correlation and heterogeneity on the outcome-diarrhoea status. Findings showed evidence of spatially varying risk imposed by social vulnerability indicators on childhood diarrhoea. We established a positive relationship between diarrhoea and water poverty, and negative association with poor sanitation and low wealth status. Spatial characterization of health effects of social vulnerability presents an important step towards targeted interventions in diarrhoea management. Our use of district level mapping provides for optimal planning and implementation, particularly, for the lowly placed individuals who are geographically located in high risk areas, since most decentralized decision making processes are made at this level.

社会脆弱性和儿童健康:贝叶斯空间模型评估马拉维儿童腹泻多重压力源的风险
儿童腹泻占非洲五岁以下儿童死亡总数的15%以上。社会脆弱性加剧了这种疾病。这项研究通过使用三个指标(水贫穷、卫生设施和资产)对社会脆弱性进行操作,以捕捉社会不利条件,衡量个人或社区资源,以预防或减轻健康影响。我们特别调查了儿童腹泻与多种压力源所产生的风险之间的关系:水贫乏、卫生条件差和低财富状况,这些因素定义了社会脆弱性。利用2013/14年马拉维千年发展目标终线调查(MMES)的数据,我们拟合了空间模型,假设社会脆弱性指标与个体协变量的综合效应在结果-腹泻状态上表现出空间相关性和异质性。调查结果显示,儿童腹泻的社会脆弱性指标所带来的风险存在空间差异。我们建立了腹泻和缺水之间的正相关关系,以及与卫生条件差和低财富状况的负相关关系。社会脆弱性对健康影响的空间特征是朝着有针对性的腹泻管理干预迈出的重要一步。我们使用的地区级别地图提供了最佳的规划和实施,特别是对于地理上位于高风险地区的底层个人,因为大多数分散的决策过程都是在这一级别进行的。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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