Regional pleural strain measurements during mechanical ventilation using ultrasound elastography: A randomised, crossover, proof of concept physiologic study

Martin Girard, Marie-Hélène Roy Cardinal, Michaël Chassé, Sébastien Garneau, Yiorgos Alexandros Cavayas, Guy Cloutier, André Y. Denault
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Abstract

Background Mechanical ventilation is a common therapy in operating rooms and intensive care units. When ill-adapted, it can lead to ventilator-induced lung injury (VILI), which is associated with poor outcomes. Excessive regional pulmonary strain is thought to be a major mechanism responsible for VILI. Scarce bedside methods exist to measure regional pulmonary strain. We propose a novel way to measure regional pleural strain using ultrasound elastography.
使用超声弹性成像测量机械通气期间的区域胸膜应变:一项随机、交叉、概念生理学研究的证明
背景机械通气是手术室和重症监护病房常用的治疗方法。当适应不良时,可导致呼吸机诱导的肺损伤(VILI),这与预后不良有关。过度的区域性肺应变被认为是造成VILI的主要机制。缺乏床边方法来测量局部肺应变。我们提出了一种利用超声弹性成像测量胸膜局部应变的新方法。
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