[Experimental animal studies of the healing of burn wounds with the use of local antimicrobials and hyperbaric O2 therapy].

W Kaiser
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引用次数: 0

Abstract

Standardized burns without experimental infection and such with infection by a constant number of bacteria of a fixed Pseudomonas-aeruginosa-strain were treated differently. Silver sulfadiazine- and Cefsulodin-cream, Polyvidon-iodine-ointment (PVP-Jod), and hyperbaric oxygen (OHP) were used to them. The courses of healing were checked by determination of the wound area daily. The best results showed the experimental uninfected untreated wounds. Wounds infected by Pseudomonas were healing most quickly by immediate and continuous application of hyperbaric oxygen. By silver sulfadiazine- and Cefsulodin-cream treated burns showed statistical significant better results than the control group. The courses of healing were significantly poorer in delayed application of OHP (only from the 8th day after the burn) or in case of therapy with PVP-iodine alone.

[使用局部抗菌剂和高压氧治疗烧伤创面愈合的实验动物研究]。
没有实验感染的标准化烧伤和由固定数量的铜绿假单胞菌菌株感染的标准化烧伤不同处理。采用磺胺嘧啶银和头孢磺定乳膏、聚维多碘软膏(PVP-Jod)和高压氧(OHP)对其进行处理。每日测定创面面积,检查愈合过程。实验中未感染、未处理的伤口效果最好。假单胞菌感染的伤口立即持续高压氧治疗愈合最快。磺胺嘧啶银和头孢氯定乳膏治疗烧伤的效果明显优于对照组。延迟应用OHP(仅从烧伤后第8天开始)或单独使用pvp -碘治疗的愈合过程明显较差。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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