Healthcare-associated Urinary tract infection and its determinants among Adult Patients Admitted to Intensive Care Units of Addis Ababa Public Governmental Hospital, Ethiopia; 2020

Wondimagegn Genaneh Shiferaw, Tigist Nega Alemu, Hindu Argeta Hailemariam, Silenat Gashaw Adibaru, Eyouel Shimeles Demissie
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Abstract

Back ground Urinary tract infections are common bacterial infections that affect almost 150 million people internationally each year. A catheter-associated urinary tract infection arises when germs enter the urinary tract via a urinary catheter, leading to infection and have been linked with increased mortality, morbidity, healthcare costs in intensive care units. It is one of the highest prevalent health care-related infections, accounting for nearly 30% of intensive care unit (ICU) reports because of its association to urinary catheterization, but has great preventive potential. Method Institutional based cross-sectional study design applied to determine the prevalence and associated factors of Health care-associated urinary tract infections among adult 391 patients admitted to ICU from 2017 to 2019 GC at Addis Ababa Public Governmental Hospital, Addis Ababa, Ethiopia, June-December 2020.Data had manually checked and entered to Epi-data manager version 4.6 and statistical analyses have been performed using SPSS version 23 software program. Strength of association between dependent and independent variables is assessed using crude odds ratio (COR) and adjusted odds ratio (AOR) with confidence Interval (CI) of 95%. Variables that had a value of P < 0.25 on bi-variate analysis were directly forward to be analyzed by multi variable analysis. Goodness of fit test had also computed for logistic regression using Hosmer and Lemeshow test resulted in (sig=0.073), finally having P-values < 0.05 is considered as statistically significant. Result the study find that the prevalence of Healthcare Associated Urinary Tract Infection among ICU admitted patients was 91(23.3%) 95%CI ;(19.2- 27.4), While length of stay, Having tracheostomy, patients on Mechanical Ventilation and taking Proton pump inhibitor drugs were associated with HAUTI in the study area. Conclusion Healthcare-associated Urinary Tract infection is highly emerging clinical condition among ICU admitted patients in the study areas.
埃塞俄比亚亚的斯亚贝巴公立医院重症监护病房成年患者保健相关尿路感染及其决定因素2020
尿路感染是一种常见的细菌感染,每年影响全球近1.5亿人。导尿管相关性尿路感染是指细菌通过导尿管进入尿路,导致感染,并与死亡率、发病率和重症监护病房的医疗费用增加有关。它是最普遍的卫生保健相关感染之一,占重症监护病房(ICU)报告的近30%,因为它与导尿有关,但具有很大的预防潜力。方法采用基于机构的横断面研究设计,对埃塞俄比亚亚的斯亚贝巴公立医院2017年至2019年ICU收治的391例成人患者进行卫生保健相关尿路感染的患病率及相关因素分析。数据已手工核对并输入Epi-data manager 4.6版本,并使用SPSS 23版本软件进行统计分析。因变量和自变量之间的关联强度采用粗优势比(COR)和调整优势比(AOR)评估,置信区间(CI)为95%。值为P <的变量;对双变量分析的0.25%直接进行多变量分析。采用Hosmer和Lemeshow检验结果进行logistic回归的拟合优度检验(sig=0.073),最终p值为<0.05被认为具有统计学意义。结果研究发现,ICU住院患者中医疗相关尿路感染的发生率为91(23.3%),95%CI为19.2 ~ 27.4,而住院时间、气管造口、机械通气和质子泵抑制剂药物与HAUTI相关。结论医疗保健相关性尿路感染是研究区ICU住院患者中高发的临床疾病。
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