The influence of sidedness in unilateral cleft lip and palate on mid facial growth at 5 years of age

Matthew John Fell, David Chong, Paras Parmar, Ting-Li Su, Lars Enocson, Bruce Richard
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Abstract

Objective: To determine whether facial growth at five years is different for children with a right versus left sided cleft lip and palate. Design: Retrospective cohort study Setting: Nine UK cleft centres Patients: Patients born between 2000-2014 with a complete unilateral cleft lip and palate (UCLP) Main outcomes measure: 5-Year-Olds Index scores Results: 378 children were included. 122 (32%) had a right sided UCLP and 256 (68%) had a left sided UCLP. 5-Year-Olds index scores ranged from 1 (good) to 5 (poor). There was a higher proportion of patients getting good scores (1 and 2) in left UCLP (43%) compared to right UCLP (37%) but there was weak evidence for a difference (Adjusted summary odds ratio 1.27, 95% CI 0.87 to 1.87; P=0.22). Conclusions: Whilst maxillary growth may be different for left versus right sided UCLP, definitive analysis requires older growth indices and arch forms.
单侧唇腭裂对5岁儿童面部中部发育的影响
目的:探讨左、右唇腭裂患儿5岁时面部发育的差异。设计:回顾性队列研究设置:9个英国唇腭裂中心患者:2000-2014年间出生的完全性单侧唇腭裂(UCLP)患者主要结局测量:5岁儿童指数评分结果:纳入378名儿童。122例(32%)为右侧UCLP, 256例(68%)为左侧UCLP。5岁儿童的指数得分从1(好)到5(差)不等。左侧UCLP获得良好评分(1分和2分)的患者比例(43%)高于右侧UCLP(37%),但证据不足(调整后的总优势比1.27,95% CI 0.87至1.87;P = 0.22)。结论:虽然左侧和右侧UCLP的上颌生长可能不同,但明确的分析需要更早的生长指数和弓形。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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