Brevundimonas spp. infection in immunocompromised children: Two case reports.

IF 1.7 Q3 INFECTIOUS DISEASES

GERMS Pub Date : 2023-03-31 eCollection Date: 2023-03-01 DOI:10.18683/germs.2023.1369

Andreé Altamirano-Beltrán, Christian Chiara-Chilet, José W López, Maria J Pons, Julio Maquera-Afaray

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Abstract

Introduction: Brevundimonas spp. are rare and opportunistic pathogens which may cause infections in patients who are immunocompromised or have underlying disease.

Case report: Two cases with a microbiological diagnosis of Brevundimonas aurantiaca and Brevundimonas spp. are presented. Both occurred in immunocompromised patients with post-chemotherapy febrile neutropenia for B-type acute lymphoblastic leukemia and hepatoblastoma. Antibiogram findings showed resistance to quinolones, ceftazidime, and intermediate resistance to cefepime, being susceptible to carbapenems and aminoglycosides. The cases responded favorably to the administration of carbapenem.

Conclusions: The identification of the species and antimicrobial susceptibility profile favor response to infection, denoting the importance of species identification and the performance of an antibiogram to determine the different susceptibility profiles described in the literature on this emerging pathogen.

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免疫功能低下儿童Brevundimonas感染:2例报告。

Brevundimonas spp是罕见的机会性病原体，可引起免疫功能低下或有基础疾病的患者感染。病例报告:两个病例与微生物诊断的aurantiaca Brevundimonas和Brevundimonas属提出。这两种情况都发生在b型急性淋巴细胞白血病和肝母细胞瘤患者化疗后发热性中性粒细胞减少的免疫功能低下患者中。抗生素检查结果显示对喹诺酮类、头孢他啶耐药，对头孢吡肟中等耐药，对碳青霉烯类和氨基糖苷类敏感。这些病例对碳青霉烯的使用反应良好。结论:物种鉴定和抗菌药物敏感性谱有利于对感染的反应，表明物种鉴定和抗生素谱在确定文献中描述的这种新兴病原体的不同敏感性谱方面的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

GERMS INFECTIOUS DISEASES-

CiteScore

2.80

自引率

5.00%

发文量