Assessing the Clinical, Economic, and Health Resource Utilization Impacts of Prefilled Syringes Versus Conventional Medication Administration Methods: Results From a Systematic Literature Review.

IF 2.3 4区 医学 Q3 PHARMACOLOGY & PHARMACY
Annals of Pharmacotherapy Pub Date : 2024-09-01 Epub Date: 2023-11-28 DOI:10.1177/10600280231212890
Dan Benhamou, Mia Weiss, Matthias Borms, Julia Lucaci, Haymen Girgis, Cecile Frolet, Wesley T Baisley, Gio Shoushi, Kristen A Cribbs, Manuel Wenk
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引用次数: 0

Abstract

Objective: The objective of this systematic review was to assess the clinical, economic, and health resource utilization outcomes associated with the use of prefilled syringes in medication administration compared with traditional preparation methods.

Data sources: We conducted a systematic literature review to evaluate outcomes such as medication errors, wastage, time savings, and contamination in prefilled syringes. Our search encompassed multiple databases, including PubMed and Embase, for studies published between January 1, 2017, and November 1, 2022.

Study selection and data extraction: Peer-reviewed publications meeting our inclusion criteria underwent rigorous screening, including title, abstract, and full-text article assessments, performed by two reviewers.

Data synthesis: Among reviewed articles, 24 met our eligibility criteria. Selected studies were primarily observational (46%) and conducted in Europe (46%). Our findings indicated that prefilled syringes consistently reduced medication errors (by 10%-73%), adverse events (from 1.1 to 0.275 per 100 administrations), wastage (by up to 80% of drug), and preparation time (from 4.0 to 338.0 seconds) (ranges varied by drug type, setting, and dosage). However, there was limited data on contamination. Economically, prefilled syringes reduced waste and error rates, which may translate into overall savings.

Relevance to patient care and clinical practice: This review highlights the value of prefilled syringes, which can streamline medication delivery, save nursing time, and reduce preventable medication errors. Moreover, prefilled syringes have the potential to minimize medication wastage, optimizing resource utilization and efficiency in health care settings.

Conclusion and relevance: Our findings provide new insights into clinical and economic benefits of prefilled syringe adoption. These benefits include improved medication delivery and safety, which can lead to time and cost reductions for health care departments, hospitals, and health systems. However, further real-world research on clinical and economic outcomes, especially in contamination, is needed to better understand the benefits of prefilled syringes.

评估预充式注射器与传统给药方法的临床、经济和卫生资源利用影响:来自系统文献综述的结果。
目的:本系统综述的目的是评估与传统制备方法相比,使用预充式注射器给药的临床、经济和卫生资源利用结果。数据来源:我们进行了系统的文献综述,以评估预充式注射器的用药错误、浪费、节省时间和污染等结果。我们检索了多个数据库,包括PubMed和Embase,检索了2017年1月1日至2022年11月1日之间发表的研究。研究选择和数据提取:符合我们纳入标准的同行评审出版物经过严格筛选,包括标题、摘要和全文文章评估,由两名审稿人进行。数据综合:在审查的文章中,有24篇符合我们的资格标准。选定的研究主要是观察性的(46%),并在欧洲进行(46%)。我们的研究结果表明,预充式注射器持续减少用药错误(10%-73%)、不良事件(每100次给药从1.1到0.275)、浪费(高达80%的药物)和制备时间(从4.0到338.0秒)(范围因药物类型、设置和剂量而异)。然而,有关污染的数据有限。从经济上讲,预充注射器减少了浪费和错误率,这可能转化为总体节省。与患者护理和临床实践的相关性:本综述强调了预充式注射器的价值,它可以简化给药,节省护理时间,减少可预防的用药错误。此外,预充式注射器有可能最大限度地减少药物浪费,优化卫生保健机构的资源利用和效率。结论和意义:我们的研究结果为采用预充式注射器的临床和经济效益提供了新的见解。这些好处包括改善药物交付和安全性,这可以减少卫生保健部门、医院和卫生系统的时间和成本。然而,需要对临床和经济结果进行进一步的实际研究,特别是在污染方面,以更好地了解预充式注射器的好处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.70
自引率
0.00%
发文量
166
审稿时长
3-8 weeks
期刊介绍: Annals of Pharmacotherapy (AOP) is a peer-reviewed journal that advances pharmacotherapy throughout the world by publishing high-quality research and review articles to achieve the most desired health outcomes.The articles provide cutting-edge information about the most efficient, safe and cost-effective pharmacotherapy for the treatment and prevention of various illnesses. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 14 days
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