[Prostaglandin E2 (PgE2) in normal and inflamed gingiva. Clinical assay. Literature review].

Q4 Dentistry
Revista Cubana de Estomatologia Pub Date : 1989-07-01
M C Alvarez Pérez, C Miyares Cao, M C Averhoff Casamayor, R Delgado Fernández, M Vera González
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引用次数: 0

Abstract

The role of prostaglandins (Pg) in the pathogeny of periodontal disease is analyzed. For that purpose, 92 samples of gingivae were taken to the same number of patients (48 women and 44 men) aged 17-74 years, and were clinically classified according to Löe gingival index. Presence of prostaglandins was determined by thin layer chromatography. Presence or absence of PgE2 was related to sex, age, Löe gingival index and degree of inflammatory infiltrated. Although correlation between Löe gingival index and degree of inflammatory infiltrate has not an exactly correspondence, the first one offers a useful initial clinical orientation. To patients with higher degree of inflammation corresponded higher PgE2 concentrations. Possibility of using prostaglandin inhibiting drugs in the treatment of periodontal disease is stated.

前列腺素E2 (PgE2)在正常和发炎牙龈中的表达。临床试验。文献综述)。
分析前列腺素在牙周病发病中的作用。为此,选取相同数量的17-74岁患者(女性48例,男性44例)的92个牙龈样本,根据Löe牙龈指数进行临床分类。用薄层色谱法测定前列腺素的存在。PgE2是否存在与性别、年龄、Löe牙龈指数、炎症浸润程度有关。虽然Löe牙龈指数与炎症浸润程度的相关性并不完全一致,但前者提供了一个有用的初步临床指导。炎症程度越高,PgE2浓度越高。前列腺素抑制药物治疗牙周病的可能性。
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来源期刊
Revista Cubana de Estomatologia
Revista Cubana de Estomatologia Dentistry-Dentistry (all)
CiteScore
0.40
自引率
0.00%
发文量
0
审稿时长
20 weeks
期刊介绍: La Revista Cubana de Estomatología fue fundada en el año 1964, dirigida a profesionales, y técnicos en el campo de la estomatología, administración de salud, y especialidades afines. Publica artículos en español, inglés y portugués en formato HTML, PDF y XML y cuenta con una Creative Commons del tipo Atribución-No Comercial 4.0 Internacional (CC BY-NC 4.0). No se cobran cargos por ninguno de los procesos editoriales o publicación de los artículos que recibimos. Misión: Publicar artículos científicos que reporten al desarrollo de las ciencias estomatológicas en beneficio de la salud de la población. Visión: Convertirse en una revista de referencia en el campo de las ciencias estomatológicas. Entre los temas que publica la Revista se encuentran: Estomatología General Integral, Periodoncia y cirugía periodontal, Prótesis dental, Cirugía maxilofacial, Implantología, Patología oral, Epidemiología, Odontopediatría, Ortodoncia, Endodoncia, Historia de la estomatología, Pedagogía, Imaginología estomatológica, Estomatología forense.
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