Limb preservation: from research to practice.

Abstract

Rodney C. Straw, BVSc, is a Diplomate in the American College of Veterinary Science and an Assistant Professor of Oncology in the School of Veterinary Medicine at Colorado State University in Fort Collins, Colorado. Spontaneously occurring neoplastic diseases in pet animals can provide valuable models for the study and evaluation of treatments for similar diseases in man. Appendicular canine osteosarcoma (OSA) is an excellent example. Canine and human OSA are similar in that the patient is generally large, slightly more males than females are affected, lesions are usually located in metaphyseal sites, stage IIB disease is most common, metastasis