[The single intercostal block--surgical and therapeutic indications].

IF 1.9 Q2 POLITICAL SCIENCE
Regional-Anaesthesie Pub Date : 1989-01-01
H C Niesel, L Klimpel, H Kaiser, S al-Rafai
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引用次数: 0

Abstract

Since the first paravertebral blockade was carried out by Sellheim in 1905, this method has proved effective for the isolated blockade of spinal nerves. The efficacy of preoperative intercostal blockade (ICB) in combination with neuroleptanalgesia (NLA) or Pentothal-pentazocine-N2O anesthesia (Pe-Pz) was studied (unilateral analgesia for cholecystectomy). Group 1: NLA; group 2: NLA with ICB; group 3: Pe-Pz; group 4: Pe-Pz with ICB. The analgesic requirement differed significantly between groups 1 (0.33 mg fentanyl) and 2 (0.15 mg fentanyl) and groups 3 (63.5 mg pentazocine) and 4 (31.5 mg pentazocine). There were also significant differences in circulatory responses. The maximum deviation from the initial value at the beginning of the operation in group 1 compared to group 2 was pulse rate + 28.7% vs + 2.4%, mean arterial pressure (Part) + 24.6% vs + 3.1%, and systolic pressure (Psyst) + 33% vs +/- 0%; group 3 compared to group 4: pulse rate + 16.4% vs + 3.2%, Part + 24.5% vs 0.0%, and Psyst + 26.5% vs + 196. The times of action of ICB extended from 7.54 h to 11.33 h for partial analgeisa, time to the first dose of analgesic from 12.3 h to 16.9 h (etidocaine 0.5% and 1% respectively without and with epinephrine). The mean blood levels after 100 mg bupivacaine-CO2 rose to 1.16 micrograms/ml after 5 min and reached a maximum after 15 min (1.29 micrograms/ml) as compared to 0.98 micrograms/ml after addition of ornithine-vasopressin. These values are very much higher than those after the use of bupivacaine-HCl solution. Etidocaine and bupivacaine-HCl have comparable durations of analgesia. Toxicologically, both substances can be applied safely with consideration of all pharmacological data for ICB. Of a total of 3,485 intercostal blockades, 2,775 were applied perioperatively (pre- and postoperatively); 265 were carried out for trauma patients (rib fractures) and 445 for therapeutic indications (herpes zoster neuralgia, tumor pain, costovertebral pain). In 8 blocks 10% ammonium sulfate, in 4 blocks absolute alcohol, and in 19 blocks 5% phenol were used for neurolysis. In 2 cases a marginal pneumothorax was seen, which was resorbed spontaneously (0.06%). Altogether 16,270 single intercostal nerves were blocked. Single-session intercostal blockade can be combined as unilateral analgesia with general anesthesia. This combination is characterized by stable circulatory conditions with avoidance of hypertensive reactions. The long-lasting analgesia allows early mobilization and physiotherapy both postoperatively and posttraumatically in patients with unilateral thoracic and abdominal pain.(ABSTRACT TRUNCATED AT 400 WORDS)

【单肋间阻滞——手术和治疗指征】。
自1905年Sellheim首次进行椎旁阻断以来,这种方法已被证明对孤立的脊神经阻断是有效的。研究术前肋间阻滞(ICB)联合神经轻镇痛(NLA)或戊二酮-戊氮唑-二氮麻醉(Pe-Pz)(单侧胆囊切除术镇痛)的疗效。第一组:NLA;第二组:NLA合并ICB;第三组:Pe-Pz;第4组:含ICB的Pe-Pz。组1 (0.33 mg芬太尼)、组2 (0.15 mg芬太尼)和组3 (63.5 mg戊唑嗪)、组4 (31.5 mg戊唑嗪)镇痛需求差异显著。两组在循环反应方面也有显著差异。与2组相比,1组与手术开始时初始值的最大偏差为脉搏率+ 28.7% vs + 2.4%,平均动脉压(Part) + 24.6% vs + 3.1%,收缩压(Psyst) + 33% vs +/- 0%;第3组与第4组比较:脉搏率+ 16.4% vs + 3.2%, Part + 24.5% vs 0.0%, Psyst + 26.5% vs + 196。局部镇痛时,ICB的作用时间从7.54 h延长至11.33 h,到第一次镇痛时间从12.3 h延长至16.9 h(分别为0.5%艾蒂多卡因和1%艾蒂多卡因,不加肾上腺素和加肾上腺素)。加100mg布比卡因- co2后,5分钟后平均血药浓度上升到1.16微克/毫升,15分钟后达到最高值(1.29微克/毫升),而加鸟氨酸-加压素后,平均血药浓度为0.98微克/毫升。这些值比使用盐酸布比卡因溶液后的值要高得多。艾蒂多卡因和盐酸布比卡因的镇痛持续时间相当。从毒理学上讲,考虑到ICB的所有药理学数据,这两种物质都可以安全使用。在总共3,485例肋间阻滞中,2,775例围手术期(术前和术后)应用;265例为外伤患者(肋骨骨折),445例为治疗指征(带状疱疹神经痛、肿瘤痛、脊柱痛)。8组使用10%硫酸铵,4组使用无水乙醇,19组使用5%苯酚进行神经松解。2例有边缘性气胸,可自发吸收(0.06%)。共有16270条肋间神经被阻断。单次肋间阻滞可作为单侧镇痛与全身麻醉联合应用。这种组合的特点是稳定的循环条件,避免高血压反应。长效镇痛使单侧胸腹疼痛患者术后和创伤后早期活动和物理治疗成为可能。(摘要删节为400字)
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CiteScore
3.50
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