[Methods for the analysis of the psychosocial behavior of the quality of life index in rats with different reconstructions after gastrectomy].

Abstract

Standardized behaviour monitoring in rats is a well-suited method for the evaluation of behavioral und nutritional effects following reconstruction surgery. Using an experimental design possible side effects resulting from the original disease can be excluded, which is an important advantage compared to clinical studies. Behavioural effects can be related to changes in biological functions following surgery. After gastrectomy 10 rats were reconstructed by Roux-Y-technique and 10 other animals by oesophagoduodenal interposition. In an open-field-behaviour-test they were compared with 10 sham operated and 10 untreated controls. Differential effects can be shown by special behavioural indices.