[The effect of withdrawal on humoral and cellular immune changes in alcoholic hepatopathy].

Abstract

In 24 patients with alcoholic hepatopathy (HA) the long-time (two years) influence--induced by the alcohol withdrawal (16 patients) or continuation (8 patients)--on the immunological, humoral and cellular modifications was followed. An important improvement of the immunological disorders, mainly the cellular ones, in the weaned patients was noticed: the increase of T lymphocytes with "reestablishment" of the T lymphocyte subsets equilibrium by increasing the T1 subpopulation--s/c: the decrease of the active T lymphocytes and of the B lymphocyte population. These changes led to humoral immune improvement. In the non-withdrawal patients, the immunological disorders continued and became even worse.