{"title":"[Effect of dopamine on small-intestinal motility in sheep].","authors":"E Cebrat, T Wegrzyn, D Zieba, Z Leroch","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The receptors involved in dopamine effect on the motility of the ileum were studied. The experiments were carried out on 3 sheep with chronic fistulas of the ileum and rumen. The contractions of the fistulated parts of the alimentary tract were recorded by the balloon method. Dopamine infused intravenously at a rate 28-38 micrograms.kg-1.min-1 inhibited the motility of the ileum. Domperidone (0.4-0.8 mg.kg-1) did not abolish this inhibiting influence of dopamine. Dopamine infused after propranolol (0.5-0.7 mg.kg-1) inhibited the motility of the ileum, however administrated after phentolamine (0.6-0.8 mg.kg-1) did not change its movements. It has been concluded that dopamine inhibits the ileum motility in sheep through alpha-adrenergic receptors.</p>","PeriodicalId":20364,"journal":{"name":"Polskie archiwum weterynaryjne","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polskie archiwum weterynaryjne","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The receptors involved in dopamine effect on the motility of the ileum were studied. The experiments were carried out on 3 sheep with chronic fistulas of the ileum and rumen. The contractions of the fistulated parts of the alimentary tract were recorded by the balloon method. Dopamine infused intravenously at a rate 28-38 micrograms.kg-1.min-1 inhibited the motility of the ileum. Domperidone (0.4-0.8 mg.kg-1) did not abolish this inhibiting influence of dopamine. Dopamine infused after propranolol (0.5-0.7 mg.kg-1) inhibited the motility of the ileum, however administrated after phentolamine (0.6-0.8 mg.kg-1) did not change its movements. It has been concluded that dopamine inhibits the ileum motility in sheep through alpha-adrenergic receptors.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
