The effect of a dentifrice containing soluble pyrophosphate and a copolymer on calculus deposit: a six-month clinical study.

T Triratana, V Kerdvongbundit, N Chutapimol, S Thepbanterng
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Abstract

A six-month, double blind, cross over clinical study was conducted to compare the effect of a commercially available anticalculus dentifrice and a placebo dentifrice on supragingival calculus deposits. Fifty adult subjects who entered the study were given an oral prophylaxis and were assigned to use either pyrophosphate/copolymer toothpaste or a placebo toothpaste for a period of three months. They were then scored for calculus deposits using the Volpe-Manhold method, received a second oral prophylaxis and used the alternate dentifrice for a second three month period of time. The subjects were again scored for calculus deposits and the study was completed. The results indicated that pyrophosphate/copolymer toothpaste reduced supragingival calculus formation by 37.07%, as compared to the placebo dentifrice. This reduction was significant at the 99% level of confidence.

含可溶性焦磷酸盐和共聚物的牙膏对牙石沉积的影响:为期六个月的临床研究。
一项为期六个月的双盲交叉临床研究进行了比较市售的抗牙石牙膏和安慰剂牙膏对龈上牙石沉积的影响。50名进入研究的成人受试者被给予口服预防,并被分配使用焦磷酸盐/共聚物牙膏或安慰剂牙膏,为期三个月。然后使用Volpe-Manhold方法对他们的牙石沉积进行评分,接受第二次口腔预防,并在第二个三个月的时间内使用替代牙膏。研究对象再次进行了微积分沉积评分,研究结束。结果表明,与安慰剂牙膏相比,焦磷酸盐/共聚物牙膏可减少龈上结石的形成37.07%。在99%的置信水平上,这种降低是显著的。
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