[A comparative study of plasma converting enzyme and renin in sarcoidosis].

Abstract

The paper reports on a comparative study of the conversion enzyme and plasmatic renin performed on a group of 55 patients, with clinical diagnosis of sarcoidosis and other lung diseases. Whereas the conversion enzyme showed important increases in active sarcoidosis and a tendency to the normal state after treatment with corticoids, the activity of the plasmatic renin remained the same, both before and after corticotherapy. The result obtained prove the practical usefulness of the dosage test of the conversion enzyme, in agreement with the literature data. They also point to the possible participation of the pulmonary SRA in the vascular and local enzymatic-chemical imbalances, suggesting the possibility of associating the conversion enzyme inhibitors to the treatment of sarcoidosis with corticoids.