{"title":"[The value of positive epicutaneous test reactions to 4,4'-diaminodiphenylmethane].","authors":"G Gailhofer, M Ludvan","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>This study was undertaken to determine the significance of positive patch test reactions to 4,4'-diaminodiphenylmethane (DDM). Data of 202 DDM-positive patients concerning age, sex and profession, type, localisation and duration of eczema and combined allergens were evaluated. The results obtained were compared by chi-square-test with those of 3397 consecutive, unselected contact dermatitis patients with negative reactions to DDM. The most conspicuous results were: 1. The positive patch test reaction to DDM is usually a marker for allergy to p-amino-compounds. 2. 39/202 patients showed isolated positive test reactions to DDM. The source of the allergen remained unclear. 3. Workers in chemical laboratories seem to have an increased risk for acquiring DDM-allergy. 4. The clinical relevance of DDM-allergy could only be proven in a few patients.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"37 1","pages":"16-22"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dermatosen in Beruf und Umwelt. Occupation and environment","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This study was undertaken to determine the significance of positive patch test reactions to 4,4'-diaminodiphenylmethane (DDM). Data of 202 DDM-positive patients concerning age, sex and profession, type, localisation and duration of eczema and combined allergens were evaluated. The results obtained were compared by chi-square-test with those of 3397 consecutive, unselected contact dermatitis patients with negative reactions to DDM. The most conspicuous results were: 1. The positive patch test reaction to DDM is usually a marker for allergy to p-amino-compounds. 2. 39/202 patients showed isolated positive test reactions to DDM. The source of the allergen remained unclear. 3. Workers in chemical laboratories seem to have an increased risk for acquiring DDM-allergy. 4. The clinical relevance of DDM-allergy could only be proven in a few patients.
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