{"title":"The use of bromodeoxyuridine-immunohistochemistry to identify transplanted fetal brain tissue.","authors":"D B Brown, B B Stanfield","doi":"10.1155/NP.1989.135","DOIUrl":null,"url":null,"abstract":"<p><p>The immunohistochemical detection of the thymidine analog, 5-bromo-2'-deoxyuridine (BrdU) is shown to be a useful and reliable method to positively identify fetal brain transplants in standard histological preparations. This technique offers several advantages over the [3H]thymidine autoradiographic method, including being much more rapid and avoiding the use of radionuclides.</p>","PeriodicalId":77739,"journal":{"name":"Journal of neural transplantation","volume":"1 3-4","pages":"135-9"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/NP.1989.135","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of neural transplantation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/NP.1989.135","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
The immunohistochemical detection of the thymidine analog, 5-bromo-2'-deoxyuridine (BrdU) is shown to be a useful and reliable method to positively identify fetal brain transplants in standard histological preparations. This technique offers several advantages over the [3H]thymidine autoradiographic method, including being much more rapid and avoiding the use of radionuclides.