[Studies of the antigenic structure of Trichophyton equinum].

Abstract

In the studies on antigenic structure of T. equinum double diffusion precipitation test in agar gel and immunoelectrophoresis were used. While preparing precipitation sera in rabbits it was manifested that the best results are achieved by immunization with live antigen. In the group of metabolic antigens and water extracts of the strains of T. equinum which were tested, 10-11 serologically+ active fractions were found whereas in protein component only L1 fraction. In comparative studies based on cross-reactivity method in which native and absorbed sera were used it was found that metabolic antigens and water extracts of T. equinum and T. mentagrophytes have 8 common fractions and only one fraction reveals species differentiation features. Two fractions, marked J and K, appeared in the studied strains of T. equinum irregularly. In protein antigen which was used in studies only one fraction (d) appeared to be common for both species, while three other fractions were separate.