Akute Pankreatitis

Peter Layer, Jutta Keller, Matthias Kahl, Ulrich Rosien
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Abstract

Manifestation of acute pancreatitis can range from a mild interstitial up to a life-threatening inflammation with necrosis inside and outside the pancreas and multiple organ failure.

Severe upper abdominal pain – often more pronounced on the left side with radiation to the shoulder and the back in a belt-like fashion – is a cardinal symptom, which – in combination with increased activity of pancreatic enzymes in the serum ≥ 3 times the upper limit of normal – leads to the diagnosis. So far, there is no specific therapy for acute pancreatitis. Treatment mainly consists of basic management, including problem-oriented measures to prevent or treat complications. Typical complications of acute pancreatitis include shock and electrolyte disorders, pleuropulmonary complications, diabetes mellitus, coagulation disorders, pseudocysts and infections. In biliary pancreatitis with concrements ERCP to remove stones should be the initial treatment. During follow-up, it is essential to identify and treat the causes of the pancreatitis.

急性Pankreatitis
急性胰腺炎的表现可以从轻微的间质性到危及生命的炎症,包括胰腺内外坏死和多器官衰竭。严重的上腹部疼痛-通常在左侧更明显,肩部和背部呈带状放射-是主要症状,与血清中胰腺酶活性增加≥3倍正常上限相结合-导致诊断。到目前为止,还没有针对急性胰腺炎的特异性治疗方法。治疗主要包括基础管理,包括以问题为导向的预防或治疗并发症的措施。急性胰腺炎的典型并发症包括休克和电解质紊乱、胸膜肺并发症、糖尿病、凝血功能障碍、假性囊肿和感染。胆道性胰腺炎合并结石,ERCP应作为首选治疗。在随访中,确定和治疗胰腺炎的病因是至关重要的。
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