Cardiorenal syndrome

Abstract

Cardiorenal syndrome (CRS) is an umbrella term that defines disorders of the heart and kidneys whereby “acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other”. The heart and the kidneys are involved in maintaining hemodynamic stability and organ perfusion through an intricate network. Dysfunction of one organ may lead to dysfunction of the other. CRS was recently sub-classified into 5 types primarily based upon the organ that initiated the insult as well as the acuity and chronicity of disease. Development of CRS is associated with increased morbidity, hospital stay, cost of healthcare and mortality. Newer biomarkers have shown potential for early diagnosis of CRS.