Temporomandibular Disorders and Fibromyalgia Prevalence: A Systematic Review and Meta-Analysis.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-11-17 DOI:10.11607/ofph.3260

Pankaew Yakkaphan, Jared G Smith, Pav Chana, Huann Lan Tan, Priya Thimma Ravindranath, Giorgio Lambru, Tara Renton

{"title":"Temporomandibular Disorders and Fibromyalgia Prevalence: A Systematic Review and Meta-Analysis.","authors":"Pankaew Yakkaphan, Jared G Smith, Pav Chana, Huann Lan Tan, Priya Thimma Ravindranath, Giorgio Lambru, Tara Renton","doi":"10.11607/ofph.3260","DOIUrl":null,"url":null,"abstract":"Purpose: To evaluate the prevalence of chronic widespread pain (CWP) and fibromyalgia syndrome (FMS) in TMD patients and the prevalence of TMDs in patients with FMS.Method: A systematic search was performed in electronic databases. Studies published in English examining the prevalence of comorbid TMDs and CWP/FMS were included. The Newcastle-Ottawa Scale was used to assess study quality, and meta-analyses using defined diagnostic criteria were conducted to generate pooled prevalence estimates.Results: Nineteen studies of moderate to high quality met the selection criteria. Meta-analyses yielded a pooled prevalence rate (95% CI) for TMDs in FMS patients of 76.8% (69.5% to 83.3%). Myogenous TMDs were more prevalent in FMS patients (63.1%, 47.7% to 77.3%) than disc displacement disorders (24.2%, 19.4% to 39.5%), while a little over 40% of FMS patients had comorbid inflammatory degenerative TMDs (41.8%, 21.9% to 63.2%). Almost a third of individuals (32.7%, 4.5% to 71.0%) with TMDs had comorbid FMS, while estimates of comorbid CWP across studies ranged from 30% to 76%.Conclusions: Despite variable prevalence rates among the included studies, the present review suggests that TMDs and CWP/FMS frequently coexist, especially for individuals with painful myogenous TMDs. The clinical, pathophysiologic, and therapeutic aspects of this association are important for tailoring appropriate treatment strategies.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664703/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.11607/ofph.3260","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: To evaluate the prevalence of chronic widespread pain (CWP) and fibromyalgia syndrome (FMS) in TMD patients and the prevalence of TMDs in patients with FMS.

Method: A systematic search was performed in electronic databases. Studies published in English examining the prevalence of comorbid TMDs and CWP/FMS were included. The Newcastle-Ottawa Scale was used to assess study quality, and meta-analyses using defined diagnostic criteria were conducted to generate pooled prevalence estimates.

Results: Nineteen studies of moderate to high quality met the selection criteria. Meta-analyses yielded a pooled prevalence rate (95% CI) for TMDs in FMS patients of 76.8% (69.5% to 83.3%). Myogenous TMDs were more prevalent in FMS patients (63.1%, 47.7% to 77.3%) than disc displacement disorders (24.2%, 19.4% to 39.5%), while a little over 40% of FMS patients had comorbid inflammatory degenerative TMDs (41.8%, 21.9% to 63.2%). Almost a third of individuals (32.7%, 4.5% to 71.0%) with TMDs had comorbid FMS, while estimates of comorbid CWP across studies ranged from 30% to 76%.

Conclusions: Despite variable prevalence rates among the included studies, the present review suggests that TMDs and CWP/FMS frequently coexist, especially for individuals with painful myogenous TMDs. The clinical, pathophysiologic, and therapeutic aspects of this association are important for tailoring appropriate treatment strategies.

查看原文本刊更多论文

颞下颌紊乱和纤维肌痛患病率:系统回顾和荟萃分析。

目的:评价慢性广泛性疼痛(CWP)和纤维肌痛综合征(FMS)在TMD患者中的患病率以及FMS患者中纤维肌痛综合征的患病率。方法:在电子数据库中进行系统检索。英文发表的研究纳入了合并tmd和CWP/FMS的患病率。使用纽卡斯尔-渥太华量表来评估研究质量，并使用定义的诊断标准进行荟萃分析，以产生汇总的患病率估计。结果:19项中高质量研究符合入选标准。荟萃分析得出FMS患者tmd的总患病率(95% CI)为76.8%(69.5%至83.3%)。肌源性TMDs在FMS患者中更为普遍(63.1%，47.7%至77.3%)，而椎间盘移位疾病(24.2%，19.4%至39.5%)，而略高于40%的FMS患者合并炎性退行性TMDs(41.8%， 21.9%至63.2%)。几乎三分之一的tmd患者(32.7%，4.5% - 71.0%)患有FMS合并症，而研究中对CWP合并症的估计从30%到76%不等。结论:尽管纳入研究的患病率各不相同，但本综述表明，tmd和CWP/FMS经常共存，特别是对于疼痛性肌源性tmd患者。这种关联的临床、病理生理和治疗方面对于制定适当的治疗策略很重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.