Synthesis and Insecticidal Activity of Novel Trifluoromethylbenzimidazole Linked N-Phenylamide Compounds

IF 2.4 3区化学 Q2 CHEMISTRY, ORGANIC

Polycyclic Aromatic Compounds Pub Date : 2024-10-20 DOI:10.1080/10406638.2023.2273885

引用次数: 0

Abstract

A series of new 5-(trifluoromethyl)-benzo[d]imidazole linked N-phenylamide compounds was designed and synthesized using 1-chloro-2-nitro-4-(trifluoromethyl)benzene as raw material via five steps. Their structures were confirmed by ¹H NMR, ¹³C NMR and HRMS. The bioassay results indicated that some of them exhibited moderate insecticidal activity (>50% inhibition) against Mythimna separata and Nilaparvata lugens at 500 μg/mL.

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新型三氟甲基苯并咪唑连接 N-苯基酰胺化合物的合成与杀虫活性

以 1-氯-2-硝基-4-(三氟甲基)苯为原料，通过五个步骤设计并合成了一系列新的 5-(三氟甲基)-苯并[d]咪唑连接 N-苯基酰胺化合物。通过 1H NMR、13C NMR 和 HRMS 确认了这些化合物的结构。生物测定结果表明，其中一些化合物在 500 μg/mL 的浓度下对 Mythimna separata 和 Nilaparvata lugens 具有中等程度的杀虫活性（抑制率为 50%）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Polycyclic Aromatic Compounds 化学-有机化学

CiteScore

3.70

自引率

20.80%

发文量

412

审稿时长

3 months

期刊介绍： The purpose of Polycyclic Aromatic Compounds is to provide an international and interdisciplinary forum for all aspects of research related to polycyclic aromatic compounds (PAC). Topics range from fundamental research in chemistry (including synthetic and theoretical chemistry) and physics (including astrophysics), as well as thermodynamics, spectroscopy, analytical methods, and biology to applied studies in environmental science, biochemistry, toxicology, and industry. Polycyclic Aromatic Compounds has an outstanding Editorial Board and offers a rapid and efficient peer review process, as well as a flexible open access policy.